bug drug

vancomycin

MRSA

daptomycin

MRSA, VRE

linezolid, tedizolid

MRSA, VRE

ceftaroline

MRSA

telavancin

MRSA

Dalbavancin

MRSA

Oritavancin

MRSA, VRE

quinupristin-dalfopristin

MRSA, VRE

tetracyclines

MRSA, atypicals

tigecycline, eravacycline, omadacycline

MRSA, VRE, anaerobes, ESBL, ampC, CRE

trimethoprim/sulfamethoxazole

MRSA, ampC

clindamycin

MRSA, anaerobes

rifampin

MRSA

delafloxacin

MRSA, p aeru, anaerobes

fosfomycin

VRE, ESBL

Nitrofurantoin

VRE, ESBL

pipercillin/tazobactam

p aeru, anaerobes

aztreonam

p aeru

aminoglycosides but not gentamicin for first guy

p aeru, ESBL, ampC, CRE

levofloxacin

p aeru, atypicals, s pneumoniae

polymyxins

p aeru, ESBL, ampC, CRE

ciprofloxacin

p aeru, atypicals

ceftazidime

p aeru

cefepime

p aeru, ampC

carbapenems (not ertapenem for first guy) and carbapenem with a beta lactamase inhibitor

p aeru, ampC, ESBL

ceftolozane/tazobactam

p aeru, ESBL

ceftazidime/avibactam

p aeru, ESBL, ampC, CRE

cefiderocol

p aeru, ESBL, ampC, CRE

amoxicillin/clavulanate

anaerobes

ampicillin/sulbactam

anaerobes, a baumanii

cefoxitin

anaerobes

cefotetan

anaerobes

carbapenems alone

anaerobes

moxifloxacin

anaerobes, atypicals

metronidazole

anaerobes

fluoroquinolones

atypicals, ESBL, ampC

macrolides

atypicals

meropenem/vaborbactam

CRE, ampc, esbl, anaerobes