2nd/3rd Trimester Placenta and Umbilical Cord (Ch. 56 & 57)

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Last updated 7:45 PM on 3/28/26
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45 Terms

1
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T/F: placenta is a multifunctional organ

True—it acts as baby’s lung (supply oxygen), kidneys (filter waste), and GI and immune systems (deliver nutrients and antibodies)

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placenta

  • major role in exchanging oxygenated maternal blood with deoxygenated fetal blood

  • develops from trophoblastic cells

<ul><li><p><span style="color: red;">major role in <strong>exchanging oxygenated maternal </strong>blood with <strong>deoxygenated</strong> <strong>fetal</strong> blood</span></p></li><li><p>develops from trophoblastic cells</p></li></ul><p></p>
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what are the functional units of the placenta?

chorionic villi

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placenta anatomy

divided into 2 parts

  1. chorionic plate (fetal surface)

  • surface facing amniotic fluid

  • continuous with chorion

  1. basal plate (maternal surface)

  • surface facing uterine wall

  • continuous with decidua basalis

<p>divided into 2 parts</p><ol><li><p><span style="color: red;"><strong><u>chorionic plate</u></strong></span> (<span style="color: red;">fetal surface</span>)</p></li></ol><ul><li><p>surface facing amniotic fluid</p></li><li><p>continuous with chorion</p></li></ul><ol start="2"><li><p><span style="color: red;"><strong><u>basal plate</u></strong> </span>(<span style="color: red;">maternal surface</span>)</p></li></ol><ul><li><p>surface facing uterine wall</p></li><li><p>continuous with <span style="color: red;">decidua basalis</span></p></li></ul><p></p>
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placenta plate facing amniotic fluid/fetus is called…

chorionic plate

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placenta plate facing uterine wall/mom is called…

basal plate

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term image
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placenta physiology: 3 functions

  • respiration (supply oxygenated blood to baby)

  • excretion (remove waste produce and deoxygenated blood)

  • nutrition

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placenta physiology: hormones

  • placenta produces and secretes:

    • HCG

    • estrogen

    • progesterone

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placenta fully develops at __ weeks

15

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what is a normal placenta size?

2 to 4 cm AP thickness

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measuring technique for placenta

  • measure in AP dimension

  • thickest portion perpendicular to uterine wall

  • DO NOT include uterine wall in measurement

  • typically measure after 23 weeks

<ul><li><p>measure in AP dimension</p></li><li><p>thickest portion <span style="color: red;">perpendicular to uterine wall</span></p></li><li><p><span style="color: red;">DO NOT include uterine wall in measurement</span></p></li><li><p>typically measure after 23 weeks</p></li></ul><p></p>
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causes for large placenta

  • diabetes

  • anemia

  • hydrops

  • torch infections

<ul><li><p>diabetes</p></li><li><p>anemia</p></li><li><p>hydrops</p></li><li><p>torch infections</p></li></ul><p></p>
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3 causes for small/thin placenta

  • infection

  • intrauterine growth restriction (IUGR)

  • aneuploidy (chromosomal abnormality)

<ul><li><p>infection</p></li><li><p>intrauterine growth restriction (IUGR)</p></li><li><p>aneuploidy (chromosomal abnormality)</p></li></ul><p></p>
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SONO: placenta

  • homogeneous

  • pebble-gray—mildly more echogenic compared to uterine wall

    • may be more echogenic in 1st trimester

  • smooth borders

  • highly vascular structure

  • rim of myometrium outside placenta should be noted

  • prominent maternal vessels may be seen posterior to placenta (anechoic tubes)

  • placental lakes may also be seen in placenta

<ul><li><p><span style="color: yellow;">homogeneous</span></p></li><li><p>pebble-gray—mildly <span style="color: yellow;">more echogenic</span> compared to uterine wall</p><ul><li><p>may be more echogenic in 1st trimester</p></li></ul></li><li><p>smooth borders</p></li><li><p>highly <span style="color: yellow;">vascular</span> structure</p></li><li><p>rim of myometrium outside placenta should be noted</p></li><li><p>prominent maternal vessels may be seen posterior to placenta (anechoic tubes)</p></li><li><p><span style="color: yellow;">placental lakes</span> may also be seen in placenta</p></li></ul><p></p>
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what to document when evaluating the placenta:

  • size/shape/position

  • cord location

  • abruption

  • hematoma

  • location (previa)

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describing placental location in uterus and in relation to cervical os

  1. in uterus

  • anterior

  • posterior

  • fundal (in uterine fundus)

  1. in relationship to cervical os

  • close to os

  • away from os

  • covering os

    • if covering internal os, that is called previa

<ol><li><p><u>in uterus</u></p></li></ol><ul><li><p><span style="color: yellow;">anterior</span></p></li><li><p><span style="color: yellow;">posterior</span></p></li><li><p><span style="color: yellow;">fundal</span> (in uterine fundus)</p></li></ul><ol start="2"><li><p><u>in relationship to cervical os</u> </p></li></ol><ul><li><p><span style="color: yellow;">close to os</span></p></li><li><p><span style="color: yellow;">away from os</span></p></li><li><p><span style="color: yellow;">covering os</span></p><ul><li><p>if covering internal os, that is called <em>previa</em></p></li></ul></li></ul><p></p>
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3 ways placenta appearance can be temporarily altered

  1. placental migration

  2. distended bladder

  3. Braxton-Hicks contraction

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placental migration

  • refers to when placenta changes position in uterine cavity

  • primarily explained by 2 theories:

    • LUS growth theory (when expanding uterus pulls placenta upward)

    • trophotropism theory (atrophic placenta in areas of low blood supply)

  • location of placenta can be identified in 1st trimester

<ul><li><p>refers to when <span style="color: red;">placenta changes position in uterine cavity</span></p></li><li><p>primarily explained by 2 theories: </p><ul><li><p><span style="color: yellow;">LUS growth theory</span> (when expanding uterus pulls placenta upward)</p></li><li><p>trophotropism theory (<span style="color: yellow;">atrophic placenta in areas of low blood supply</span>)</p></li></ul></li></ul><ul><li><p>location of placenta can be identified in 1st trimester</p></li></ul><p></p>
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distended bladder

  • changing bladder shape can create appearance of placental movement or a change in placental shape

  • full bladder can elongate cervix and give false impression of previa

  • emptying bladder allows cervix to be in normal position

** have patient empty bladder and reimage if previa is seen

<ul><li><p>changing bladder shape can create appearance of placental movement or a change in placental shape</p></li><li><p><span style="color: red;">full bladder can elongate cervix and give false impression of previa</span></p></li><li><p><span style="color: yellow;">emptying bladder</span> allows cervix to be in normal position </p></li></ul><p></p><p>** have patient empty bladder and reimage if previa is seen</p><p></p>
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Braxton-Hicks contraction

  • practice/false contractions

  • transient myometrial (uterine wall) contraction

  • created appearance of a placenta mass (distorts placenta shape)

<ul><li><p>practice/false contractions</p></li><li><p>transient myometrial (uterine wall) contraction</p></li><li><p><span style="color: red;">created appearance of a placenta mass</span> (distorts placenta shape)</p></li></ul><p></p>
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placental PW doppler and SONO evaluation

uterine artery PW (varies based on trimester):

  • high RI flow pattern in 1st trimester

  • low RI flow pattern in 2nd trimester

    • lots of blood flow going through uterine artery to get to placenta and supply baby with oxygen

SONO evaluation:

  • use optimal gate, gain, scale, placement

  • measure waveform and RI

<p>uterine artery PW (varies based on trimester):</p><ul><li><p>high RI flow pattern in 1st trimester</p></li><li><p>low RI flow pattern in 2nd trimester</p><ul><li><p>lots of blood flow going through uterine artery to get to placenta and supply baby with oxygen</p></li></ul></li></ul><p>SONO evaluation:</p><ul><li><p>use optimal gate, gain, scale, placement</p></li><li><p>measure waveform and RI </p></li></ul><p></p>
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4 permanent placental variations

  1. succenturiate lobe

  2. circumvallate or circummarginate

  3. battledore cord insertion

  4. velamentous cord insertion

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succenturiate lobe

  • aka accessory placental lobe

  • one or more accessory placental lobes

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circumvallate or circummarginate

  • rare (1-2% of pregnancies)

  • chorionic plate (fetal side) is smaller than normal —> amnion and chorion membranes fold back around the edges of placenta

    • ”double back”

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battledore cord insertion

  • aka marginal cord insertion

  • cord attaches at edge of placenta

  • “battledore” means badminton racket —> placenta is woven racket and cord is the handle

  • 7-9% of pregnancies

  • MC in twins

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battledore cord insertion is usually ok, but could lead to…

  • IUGR (intrauterine growth restriction)

  • preterm labor

  • fetal distress during labor

  • risk of placental abruption

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velamentous cord insertion

  • RARE (0.1-0.8 of pregnancies)

  • cord attaches to fetal membranes (amnion and chorion) increase of placental disc

  • fetal arteries and vein are UNPROTECTED by Wharton’s Jelly at insertion

  • high risk of cord compression, trauma, and rupture—especially during labor

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delayed umbilical cord clamping

  • babies are born with 2/3 of their blood

  • 1/3 of their blood is still in placenta

  • umbilical cord clamping/cutting is not done immediately after birth

    • wait 30-60 seconds after birth to allow more blood to transfer from placenta to baby

  • benefits:

    • babies have higher hemoglobin

    • higher iron

    • better transition to breathing outside

** now a widely recommended as standard care

<ul><li><p>babies are born with 2/3 of their blood</p></li><li><p>1/3 of their blood is still in placenta</p></li><li><p>umbilical cord clamping/cutting is not done immediately after birth</p><ul><li><p>wait 30-60 seconds after birth to allow more blood to transfer from placenta to baby</p></li></ul></li><li><p>benefits:</p><ul><li><p>babies have higher hemoglobin</p></li><li><p>higher iron</p></li><li><p>better transition to breathing outside </p></li></ul></li></ul><p></p><p>** now a widely recommended as standard care</p>
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umbilical cord

  • connecting yolk stalk and allantois ducts become the umbilical cord

    • allantois connect to fetal bladder (abdominal/fetal cord insertion point)—becomes belly button

  • allantoic vessels become umbilical vessels

  • surrounded by mucoid connective tissue: Wharton’s Jelly

  • cord covered by amniotic membranes

  • normal diameter: 1-2 cm

<ul><li><p>connecting <span style="color: yellow;">yolk stalk </span>and <span style="color: yellow;">allantois ducts become</span> the <span style="color: yellow;">umbilical cord</span></p><ul><li><p>allantois connect to fetal bladder (abdominal/fetal cord insertion point)—becomes belly button</p></li></ul></li><li><p>allantoic vessels become umbilical vessels</p></li><li><p><span style="color: red;">surrounded by mucoid connective tissue: Wharton’s Jelly</span></p></li><li><p>cord covered by amniotic membranes</p></li><li><p><span style="color: red;">normal diameter: 1-2 cm</span></p></li></ul><p></p>
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umbilical cords have how many vessels

  • 2 smaller arteries, 1 large vein

  • single umbilical artery (2 vessel cord) is found in 1% of singleton births

    • can be isolated

    • can be associated with congenital malformation

** umbilical arteries and vein functions opposite from typical a. and v.

<ul><li><p><span style="color: rgb(255, 115, 115);">2 smaller arteries</span>, <span style="color: rgb(120, 156, 255);">1 large vein</span></p></li><li><p>single umbilical artery (2 vessel cord) is found in 1% of singleton births</p><ul><li><p>can be isolated</p></li><li><p>can be associated with congenital malformation</p></li></ul></li></ul><p></p><p>** umbilical arteries and vein functions opposite from typical a. and v.</p>
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umbilical arteries

  • 2 umbilical arteries carry deoxygenated blood from fetus to placenta

    • umbilical arteries can be noted on either side of bladder at fetal insertion

<ul><li><p>2 umbilical arteries carry <span style="color: red;">deoxygenated</span> blood from fetus to placenta</p><ul><li><p>umbilical arteries can be noted on either side of bladder at fetal insertion</p></li></ul></li></ul><p></p>
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umbilical vein

1 umbilical vein carries oxygenated blood from placenta to fetus

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umbilical cord color Doppler

  • color Doppler is used to visualize umbilical arteries and vein

  • the bladder, when full, is seen between 2 umbilical arteries

  • umbilical cord should be images in cross section and with color Doppler at level of bladder to confirm the number of cord vessels

<ul><li><p>color Doppler is used to visualize umbilical arteries and vein</p></li><li><p>the bladder, when full, is seen between 2 umbilical arteries</p></li><li><p>umbilical cord should be images in cross section and with color Doppler at level of bladder to confirm the number of cord vessels</p></li></ul><p></p>
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<p>type of placenta?</p>

type of placenta?

succenturiate lobe (accessory placenta)

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<p>type of placenta?</p>

type of placenta?

circumvallate/circummarginate (chorionic plate is smaller than basal plate —> folded membranes)

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<p>type of placenta?</p>

type of placenta?

battledore cord insertion (umbilical cord attaches to edge of placenta, rather than center)

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<p>type of placenta?</p>

type of placenta?

velamentous cord insertion (umbilical cord inserts into fetal membranes rather than placenta)

<p><span style="color: yellow;">velamentous cord insertion</span> (umbilical cord inserts into fetal membranes rather than placenta)</p>
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<p>type of placenta?</p>

type of placenta?

battledore cord insertion

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chorion frondosum

“portion of chorion that develops into fetal portion of the placenta” (chorionic plate)

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chorionic villi

“microscopic vascular projections from chorion that combine with maternal uterine tissue to form placenta”

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which part of the decidua surrounds the chorionic sac?

decidua capsularis

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which part of the decidua unites with the chorion to form the placenta?

decidua basalis

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placenta accreta vs. placenta increta vs. placenta percreta

placenta accreta

  • growth of chorionic vlli superficially to myometrium; not does penetrate through myometrium

placenta increta

  • growth of chorionic villi deep into myometrium

placenta percreta

  • growth of chorionic villi through the myometrium to the uterine serosa

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Wharton’s jelly

mucoid connective tissue that surrounds the vessels within umbilical cord

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