AP Bio Unit 1 - Chemistry of Life by Kori

Hypothesis: an explanation to a question, tested by an experiment or continues observation

Hypotheses can be disproven but not proven true

Theory: summarizes a group of hypotheses

Theories never become a law

Inductive reasoning: a process of reasoning going from specific to broad

Deductive reasoning: a process of reasoning going from broad to specific

Experimental group: a group that is tested with a changed variable

Scientific Law: statement of fact usually as a mathematical formula

Control Group: expected results of an experiment

Constants: all the factors that stay the same in an experiment

Mean: average of the data set

Median: middle number in a range of data points

Mode: value that appears most often in a data set

Independent variable: one factor that is changed or manipulated

Dependent variable: factor which is measured

Null hypothesis: no difference between two groups of data and experimental observations due to chance

Alternative hypothesis: opposing theory to the null hypothesis

Central tendencies: statistical measures that describe data trends

Variability: measure of how far a data set diverges from central tendency

Range: difference between largest and smallest values

Larger range is greater variability

Smaller range is less variability

Standard deviation: measure of how spread out the data is from the mean

Low standard deviation means data is closer to the mean, IV causes changes

High standard deviation means the data is farther from the mean, other factors cause changes

Standard error of the mean: determine precision and confidence in mean value

What is the difference between inductive and deductive reasoning? Inductive is specific to broad and deductive is broad to specific

What is the difference between a theory and a law? A theory summarizes a group of hypothesis while laws state scientific facts, usually a math equation

How are hypotheses formulated? They are formulated from a question to be proven or disproven, stating a null hypotheses and alternate hypotheses

What is the difference between null and alternative hypotheses? Null hypotheses state a hypotheses that suggests no effect or difference between variables, where alternative hypotheses propose different possible outcomes

Do you always need a null and alternate hypothesis? You need both null and alternate hypothesis because it tests all possibilities in the experiment and clarifies to focus of the experiment

How do researchers determine their independent and dependent variables? Independent and dependent variables are determined from what needs to be tested and what needs to remain consistent through the experiment, limiting variables

How are variables often graphed? Dependent variables are graphed on the y-axis and independent are graphed on the x-axis

Are constants the same as controls? No, they are not the same, because constants are factors/variables that do not change while controls are groups that serve as the standard of comparison

When should a positive control be used? A positive control should be used to compare experimental exposure to a known, effective exposure

When should a negative control be used? A negative control should be used to compare the effectiveness of exposure to no exposure

What types of data can be collected in an experiment? Quantitative (measured with instruments) and qualitative (measured with senses)

When should mean be used? Mean should be used to average the data and find a typical value to be compared to

When should median be used? Median should be used when a data set has extreme values or abnormal distribution

When should mode be used? Mode should be used when describing the distribution of data where mean and median are not appropriate

What is used to measure variability? Range and standard deviation measures variability

Is data more reliable with low or high standard deviation? Data is more reliable with a low standard deviation because it is closer to the mean and thus suggests that only the independent variable is causing data changes

Why do researchers use SEM? SEM is used because it verifies the accuracy of the mean

If error bars overlap, is the data significantly different? If error bars overlap, the data is not significantly different

Matter: takes up space and has mass

Element: matter cannot be broken down

Compound: Two or more elements

Octet rule: atoms gain, lose, or share electrons to achieve a stable 8 electrons

Capillary action: upward movement of water, occurs when adhesion is greater than cohesion

Chemical bonds: two atoms sharing the transfer of a valence electron

Hydrogen bonds: charged hydrogen in a polar covalent molecule, strongest bond

Covalent bond: two or more atoms sharing electrons

Polar: not equally shared

Nonpolar: equally shared

Ionic bonds: oppositely charged bonds, usually a metal and nonmetal

Cohesion: attraction of molecules for the molecules of the same kind

Electronegativity: atom’s ability to attract electrons

Adhesion: Clinging of one molecule to a different molecule

Atomic mass: number of protons + neutrons

Solute: product that the solvent dissolves

Solution: product of solute and solvent

Solvent: dissolving agent in a solution

Valence electrons: outmost electrons in outmost valence shells

Molecule: atoms bonded together

Acid: molecule that can donate or accept a proton

Base: molecule that can accept hydrogen ions in water

What is the difference between a solute, solvent, and solution? Solute is dissolved, solvent dissolves the solute, and the solution is the product

What are two examples of covalent bonds? Carbon dioxide, glucose

What are two examples of ionic bonds? Sodium chloride, lithium fluoride

Hydrogen bonds are different from other bonds because they bond to a Hydrogen ion in a polar covalent molecule, they are also the weakest

How does electronegativity affect the interactions between water molecules? Oxygen pulls electrons and hydrogen closer and causes polarity in the molecules

If O and H had the same electronegativity, what would that do to the properties of water? Hydrogen would not be pulled as close to Oxygen and the water would not be polar

Adhesion: attractive forces between molecules of different types

Cohesion: attractive forces between molecules of the same type

Surface tension: adhesion that allows liquid to condense and resist external force

Adhesion can benefit plant cells by penetrating the cell wall

Cohesion can benefit plants by moving water up the xylem against gravity

Surface tension can benefit organisms that float on water

Functional groups: chemical groups attached to carbon skeleton that participate in chemical reactions

Organic chemistry: study of compounds with covalently bonded carbon

Organic compounds: compounds that contain Carbon and Hydrogen

Hydrocarbons: organic molecules of only carbon and hydrogen

ATP: Adenosine triphosphate, a source of energy and storage at a cellular level

Macromolecule: compounds such as carbohydrates, proteins, nucleic acids, and lipids

Hydroxyl GroupAmino GroupPhosphate GroupSulfhydryl (Thiol) GroupCarbonyl GroupMethyl Group

Why is carbon such a versatile element? It can form long chains and carbon skeletons to support organic molecules

Lewis dot carbon molecule

How many valence electrons does carbon have? 4

How do functional groups affect the structure and behavior of organic molecules? It affects the reactivity and polarity of an organic molecule

What is the difference between hydrocarbons and other organic molecules? Hydrocarbons only contain Carbon and Hydrogen, while other organic molecules contain Carbon, Hydrogen, and Oxygen

Dehydration reaction: bonds two monomers with the loss of H2O

Hydrolysis: breaks bonds by adding H2O

Polymers: chain-like macromolecules of similar or identical repeating units

Monomers: repeating units that make up polymers

Differentiate between a hydrolysis and dehydration reaction. Hydrolysis breaks bonds by adding H2O, as the Hydrogen in H2O bonds to a monomer and OH bonds to the other monomer. Dehydration reaction bonds two monomers with the loss of H2O as OH of one monomer bonds to H as H2O is produced and released

Dehydration reactionHydrolysis

Disaccharide: two monosaccharides joined by covalent bonds

Monosaccharide: simple sugars formed with multiple units of CH2O

Polysaccharide: polymer with many sugars joined via dehydration reactions

Carbohydrate: sugars and polymers of sugars containing a carbonyl group and many hydroxyl groups made of Carbon, Hydrogen, and Oxygen

Proteins: molecules consisting of polypeptides folded into a 3D shape

Amino Acids: molecules that have an amino group and a carboxyl group

Polypeptide: many amino acids linked by peptide bonds

Cellulose: polysaccharide that is the structural component of the cell wall

Glycogen: polysaccharide of glucose stored in the body as an energy storage

Hydrophobic: repel water

Hydrophilic: attracts water

Glycosidic linkage: covalent bonding connecting a carbohydrate to another group

Starch: polysaccharide of glucose stored as energy in plants

How many monomers of proteins are there? 20

Amino Acid

How do the R groups of amino acids contribute to the protein structure? They interact and determine the shape and function of the protein

Phospholipid

The hydrophilic head is polar

The hydrophobic tails are nonpolar

Where can phospholipids be found in a cell? They are found in the cell membrane

What role do phospholipids perform? They allow cellular processes to happen by signaling proteins and protect the cell from outside offenses

What are the monomers of polysaccharides? Monosaccharides bonded by glycosidic bonds

How are polysaccharides important to animals and plants? They can store starch and glycogen and form cellulose or chitin

How does saturation affect fatty acid structure and function? Saturated fats have no double bonds which allows more hydrogen and decreases fluidity

Carbohydrate

What elements are found in Carbohydrates? Carbon, Hydrogen, and Oxygen

Protein polypeptide

What elements are found in proteins? Carbon, Hydrogen, Oxygen, Nitrogen, and Sulfur

Nucleic Acid

What elements are found in nucleic acids? Carbon, Hydrogen, Oxygen, Nitrogen, Phosphorus

Saturated LipidUnsaturated Lipid

What elements are found in lipids? Carbon, Oxygen, and Hydrogen

Primary Structure: linear chain of amino acids determined via genes, dictating secondary and tertiary forms

Secondary Structure: coils up and folds due to hydrogen bonding within the backbone of the polypeptide

Tertiary Structure: 3D folding due to interactions between the side chains of the amino acids

Quaternary Structure: association of two or more polypeptides only found in some proteins

Lipid: class of small, nonpolar molecules that do not include true polymers

Fats: composed of glycerol and fatty acids

Fatty Acid: long carbon chains with a carboxyl group at the end

Phospholipid: component of cell membranes, two fatty acids attached to glycerol and phosphate

Denature: unfolding of a protein and modifying the structure

Steroid: molecules that regulate cellular functions like reproduction and development

How was the double helix structure of DNA discovered? X-Ray diffraction by Rosalind Franklin showed the shadow of two helixes in DNA

What forms the backbone of DNA? Sugar-phosphate backbone

Why are DNA strands antiparallel? DNA strands are complementary to each other from base pairing

What determines the primary structure of a protein? The sequence of amino acids

How does the primary structure affect the other structural levels? The location of certain amino acids in the primary structure lays the foundation for the shape of other structural levels

Would the function of a protein change if the amino acid sequence changed? Some changes may not have any different results but some can result in a protein losing its function

What interactions occur in the secondary structure? Hydrogen bonding of polypeptides

What interactions occur in the tertiary structure? Outside polar hydrophilic hydrogen and ionic bond interactions and internal hydrophobic interactions between nonpolar amino acid side chains

What interactions occur in the quaternary structure? Ionic bonding, hydrogen bonding, disulfate bonds, and dispersion forces

What causes a protein to denature? Chemical action, heat, or agitation

What happens to a protein if it is denatured? It cannot function as the primary structure is destroyed and the protein is broken down to monomers

What macromolecule would both starch and cellulose be considered? A carbohydrate

Antiparallel: DNA strands run in opposite directions parallel to one another 3’-5’

DNA: deoxyribonucleic acid, carries genetic information for the development and functioning of an organism

RNA: ribonucleic acid, a nucleic acid used to produce proteins

Nucleotide: compound of a nitrogenous base, pentose, and a phosphate group which acts as a monomer for nucleic acids

Nucleic Acid: polymers made of nucleotides which function as storage, transmitters, and expression of hereditary information

Genes: basic unit of heredity passed from parent to child made of DNA sequences

Pyrimidine: One ring with 6 atoms (Cytosine, Thymine, Uracil)

Purine: One ring with 6 atoms bonded to another ring with 5 atoms (Adenine, Guanine)

What are the three components of a nucleotide? Nitrogenous base, pentose sugar, and phosphate group

What is the monomer called if it is lacking a phosphate group? A nucleotide

What are the possible nitrogenous bases that can be found in nucleotides? Adenine, Thymine, Guanine, Cytosine, Uracil

What does DNA have that RNA does not? It has a double helix, deoxyribose, uses thymine, and stores/transfers genetic information

What does RNA have that DNA does not? It has a single helix, ribose, uses uracil, and codes proteins

Where can DNA be found in a cell? Cell nucleus

Where can RNA be found in a cell? Cytoplasm or nucleus

What functional group defines the 5’ end? Phosphate group

What functional group defines the 3’ end? Hydroxyl group