Glucose Transporters, location and importance

Where is GLUT 1 found?

Blood, blood brain barrier, heart

Where is GLUT 2 found?

Liver, pancreas, small intestine

Where is GLUT 3 found?

Brain, neurons, sperm

Where is GLUT 4 found?

Skeletal muscle, adipose tissue, heart

Where is GLUT 5 found?

Enterocytes of intestines, epithelium

Where is SGLT 1 found?

Enteroccytes of intestines, epithelium

Where is SGLT 2 found?

Proximal tubule of nephrons

GLUT 1 function

Reuptake of glucose

GLUT 2 function

Reuptake and release of glucose

GLUT 3 function

Uptake of glucose in brain, kidney and placenta

GLUT 4 function

Insulin stimulated uptake of glucose in heart, skeletal muscle and adipose tissue

GLUT 5 function

Absorption of glucose in small intestines

SLGT1 function

Active uptake of glucose from lumen of intestineand reabsorption of glucose