serological detection of microorganisms

an organisms ability to establish infection

infectivity

an organisms ability to cause disease

pathogenicity

total set of proteins expressed by an organism

proteome

this technology ionizes a sample of a target organism and analyzes the ions based on size and charge

mass spectrometry

strep species can be separated into groups based on special carbohydrates that are embedded in thier cell wall, these groups are called what?

Lancefield

this test relys on the hemolysis of red blood cells and indicates a recent infection with strep pyogenes

anti-streptolysin O

this test is an agglutination assay that tests for antibodies against 5 different antigens found on S. pyogenes

streptozyme

this, along with the urea breath test are useful in diagnosing an infection with H.pylori

CLO-test

this type of infection with Mycoplasma pneumoniae, the top layer of the skin dies and falls off

Stevens-Johnson syndrome

detection of cold agglutinins is useful in diagnosing an infection with what?

mycoplasma pneumoniae

this organism has the ability to coat itself in host proteins and effectively evade the host immune system for years, causing a multistage and potentially latent infection

Treponema pallidum

VRDL and RPR testing do not actually detect antibodies to T. pallidum,, what do these assays really detect?

anti-cardiolipin

the weil-felix test, relies on the cross reactivity of antibodies to what organism and antigens found on Proteus vulgaris?

Rickettsia rickettsiae

natural barriers, PAMPs an enzymes like lysosome are all part of what?

innate immunity

when doing a viral cell culture, host cells are grown in vitro and inoculated with patient specimen, what is the change that we monitor the cells for called?

cytopathic effect

what type of molecular testing is used to monitor viral load in diseases such as HIV?

QPCR

these antibodies react with antigens of a different species. this phenomenon is used as the basis in a test for infectious mono

heterophile antibodies

this organism causes vesicular lesions and has the potential to lay dormant for years, if triggered again, the reemerging infection is called Shingles

Varicella Zosters

this organism is a single stranded RNA virus that is highly contagious and causes a red rash. Koplik spots can be a hallmark sign of this organism

Rubeola

this is the most prevalent sexually transmitted viral infection

papillomaviruses

if left untreated, HTLV1 and 2 have the potential to progress to what disease state?

leukemia/lymphoma

infections caused by this virus are typically self-limiting, however, in neonates this organism has the potential to cause platelet dysfunction and CNS problems

cytomegalovirus

this group of viruses contains large, enveloped DNA viruses that have the potential to cause latent infection later in life

Herpes viruses

CagA and VacA are virulence factors used as targets to identify what organism?

Helicobacter pylori

Lipid A, cytotoxins, neurotoxins, and enterotoxins are all examples of what?

virulence factors