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what is a simple definition of organs
communities of specialised cell types
what is cell differentiation
the process by which unspecialised cells become specific cell types
how do cells differ
based on the presence of different proteins, different metabolites, different morphologies and behaviours
where are chromaffin cells found
within the adrenal glands
give a brief overview of chromaffin cells
produce the hormone epinephrine, contain large numbers of vesicles containing epinephrine, contain the enzyme that converts tyrosine into norepinephrine and epinephrine
when do chromaffin cells release epinephrine into the bloodstream
upon simulation from the autonomic nervous system
what do cell lineages refer to
the developmental history of the cell
what does lineage restriction refer to
as cells become more specialised, the number of cells they can become is restricted
what is developmental potency
unspecialised cells in the early embryo are pluripotent, can form any cell type, multipotent cells can differentiate into many different cell types but not all
what is terminal differentiation in simple terms
when differentiation ends, the final cell form
what are the different germ layers
ectoderm, mesoderm, endoderm
when are germ layers formed
during gastrulation
how are mesoderm cells more differentiated
by the presence of specific proteins, characteristic cell behaviour, restricted future differentiation potential
do mesoderms exist in the final organism
no
what is gastrulation
the formation of germ layers by invagination
where are HSCs found
in the bone marrow
what does the endoderm develop into
several different internal organs
can the nucleus of differentiated cells support the development of a new organism
yes, this was first shown in frogs but can be done in plants and mammals
what is gene constancy
all cells in multicellular organisms have a full complement of genes
how can gene expression be controlled
DNA may be transcribed from all genes but RNA is degraded in cells that do not require it or the DNA may just not be transcribed