Contraindications to Thrombolytics

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Relative or Absolute:
Prior intracranial hemorrhage

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1

Relative or Absolute:
Prior intracranial hemorrhage

Absolute

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2

Relative or Absolute:
Known cerebral vascular lesion

Absolute

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3

Relative or Absolute:
Known malignant intracranial neoplasm

Absolute

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4

Relative or Absolute:
Ischemic stroke within 3 month

Absolute

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5

Relative or Absolute:
Suspected aortic dissection

Absolute

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6

Relative or Absolute:
Active bleeding or bleeding diathesis (except menses)

Absolute

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7

Relative or Absolute:
Significant closed head or facial injury within 3 months

Absolute

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8

Relative or Absolute:
Hx of chronic, severe, or poorly controlled HTN

Relative

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9

Relative or Absolute:
Severe uncontrolled HTN on presentation (SBP > 180 mmHg or DBP > 110 mmHg)

Relative

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10

Relative or Absolute:
Hx of prior ischemic stroke > 3 months or dementia

Relative

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11

Relative or Absolute:
Recent traumatic or prolonged cardiopulmonary resuscitation or major surgery (< 3 weeks)

Relative

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12

Relative or Absolute:
Recent (2-4 weeks) internal bleeding

Relative

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13

Relative or Absolute:
Noncompressible vascular punctures

Relative

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14

Relative or Absolute:
For streptokinase or anistreplase: prior exposure (> 5 days ago) or prior allergic reaction

Relative

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15

Relative or Absolute:
Pregnancy

Relative

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16

Relative or Absolute:
Active peptic ulcer

Relative

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17

Relative or Absolute:
Current use of anticoagulants

Relative

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