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azidothymidine/zidovudine
#1 drug used to treat HIV
decreases viral load
increases CD4 T-cell
side effects of azidothymidine/zidovudine
severe anemia & neutropenia
liver damage
education for azidothymidine/zidovudine
monitor liver enzymes
CBC
lopinavir/ritonavir & fosamprenavir
protease inhibitors
side effects of lopinavir/ritonavir & fosamprenavir
hyperglycemia & causes diabetes mellitus
lipodystrophy (fat deposits)
hyperlipidemia - elevated cholesterol
education for lopinavir/ritonavir & fosamprenavir
tolerated best at bedtime
avoid high fat meals
monitor liver enzymes, lipid panel, & blood glucose
efavirenz
non-nucleoside reverse transciptase inhibitors (NNRTIs)
side effects of efavirenz
teratogenic effect
dizziness, insomnia, strange dreams
hepatotoxicity
education for efavirenz
liver enzymes
avoid high fat meals
do not give to pregnant women
raltegravir
integrase strand transfer inhibitors (INSTIs)
commonly used in combination
side effects of raltegravir
elevation in liver enzymes
elevation in serum amylase & lipase - pancreatitis
education for raltegravir
AST, ALT
amylase & lipase
CD4 T-cell count
acyclovir
topical, PO, IV
treatment for acyclovir
HSV (herpes simplex virus) type 1 & 2
varicella zoster virus
side effects of acyclovir
IV therapy
reversible nephrotoxicity
oral therapy
GI
education for acyclovir
infuse IV slowly with extra fluids
BUN & creatinine
no cure