Structure and Cellular Organization of Tissues

This set of flashcards covers key vocabulary and concepts related to the structure and cellular organization of tissues, focusing on cell adhesion molecules, the extracellular matrix, and related functions.

Cell-Adhesion Molecules (CAMs)

Proteins that enable animal cells to adhere tightly and specifically to other cells.

Extracellular Matrix (ECM)

A complex network of proteins and carbohydrates secreted by animal cells, providing support and binding cells in tissues.

Cadherins

A family of Ca2+-dependent CAMs that play a critical role in cell-cell adhesion during tissue differentiation.

Immunoglobulin Superfamily (Ig) CAMs

Ca2+-independent cell-cell adhesion proteins that mediate homophilic interactions.

Selectins

CAMs that mediate adhesion between leukocytes and the endothelium, dependent on Ca2+ ions.

Integrins

Alpha-beta heterodimeric proteins that mediate cell-extracellular and cell-cell interactions.

Extravasation

The movement of leukocytes from the blood into underlying tissue at sites of infection.

Fibronectin

An extracellular matrix glycoprotein that binds to integrins and helps in wound healing.

Proteoglycans

Molecules composed of polysaccharides that are key components of the extracellular matrix.

Gap Junctions

Channels that allow communication and the passage of ions and small molecules between adjacent cells.