Primary adrenocortical insufficency
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5 Terms
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Primary cause
Addison disease
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less common cause
Tuberculosis
HIV, AIDS
Sarcoidosis (a chronic inflammatory disease characterized by the formation of granulomas)
Radiation therapy
Adrenal hemorrhage
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Pathogenesis
Dysfunction of adrenal cortex
Leads to deficiency of adrenocortical hormone
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Etiology
Autoimmune disease
Antibodies to 21-hydroxylase
Tuberculosis
Other infiltrative processes
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Clinical manifestation
Hypotension (main sign), dehydration, hypoglycemia [hyponatremia (low sodium) hyperkalemia (high potassium)]
Fatigue, weakness
Weight loss, anorexia, nausea, vomiting
Abdominal pain (diarrhea or constipation)
Note 
Flashcards (20)