Environmental factors that facilitate cancer

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4 Terms

1
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How does ultraviolet (UV) light facilitate cancer?

UV light can cause pyrimidine dimers that interfere with DNA polymerase, leading to improper base incorporation.

2
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What is the effect of pyrimidine dimers on DNA?

Pyrimidine dimers distort the DNA helix, preventing proper DNA polymerase function.

3
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How can ionizing radiation facilitate cancer?

Ionizing radiation causes DNA breaks, increasing the chance of errors during DNA repair.

4
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What type of DNA repair is commonly affected by ionizing radiation-induced breaks?

Nonhomologous end joining is often affected by DNA breaks caused by ionizing radiation.