Geriatrics

What is least impacted by aging

Gi absorption

What is the effect of aging on IM absorption

decreased

What is the effect of aging on transdermal absorption

Decreased

What type of medications have an increased volume of distribution

Lipid soluble medications

What is the effect of aging on protein binding

Decreased protein in body might mean more free drug in the body such as Phenytoin and Warfarin

What values need to be assessed for drug dosing

CrCl and eGFR

What is table 2 of beers

Medications that should be avoided

What is table 3 of beers

Medications that should be avoided in person know to have specific disease or syndromes

What is table 4 of beers

Medications that should be used with caution

What medications are associated with falls

Opioids

Alpha Blockers

Diuretics

Digoxin

Benzodiazepene

What are the effects of anticholinergics on the elderly

Dry eyes, dry mouth, blurred vision, delirium

What medications have anticholinergic side effects

Antihistamines

Phenothiazines

Which type of arthritis is common in geriatric

OA

Which conditions are risk for falls

OA

Glaucoma

UTI

orthostatic hypotension

What medications to avoid

• centrally acting agents

• a blockers

What medications are preffered

Low dose diuretics

ACE Inhibitors

ARBs

Calcium channel blockers

Which drugs are NOT first line in AFIB

Digoxin and Amiodarone

True or false Asprin is used for primary prevention

False

What is preffered for cerbrovascular disease

Asprin, Clopidogrel and Aggrenox

What should be used to aid Insomnia

Melatonin

What medications to avoid in diabetes

• Sulfonylureas -Glyburide and glimepride

• Glitazones—thiazolidinediones

• Flozins

What to use for GERD

Proton pump inhibitors

What to use for urinary incontinence

Mirabegron and Vibegron

What to avoid for benign prostatic hyplasia

Nonselective a1 blockers

What drugs are the most problematic

Fat soluble because they stay in the body longer