Obesity Study guide

GLP-1 REMS

Thyroid C-Cell tumors, acute pancreatitis

GLP-1 contradictions

Hx of thyroid cancer, Endocrine neoplasia type II

Phentermine contradictions

Tolerance, alcohol use, diuretics, hepatic dysfunction, Hx of drug abuse, CVD, Hyperthyroidism, glaucoma, use of MAOI in past 14 days

Phentermine/Topiramate (Qsymia) contradictions

Tolerance, alcohol use, diuretics, hepatic dysfunction, Hx of drug abuse, CVD, Hyperthyroidism, glaucoma, use of MAOI in past 14 days

Bupropion/Naltrexone (Contrave) contradictions

High fat meals, Antipsychotics, Clopidogrel, Seizures, HTN, eating disorder, Chronic opioid use

Orlistat (Xenical) contradictions

Take w/ multivitamin, cholestasis, malabsorption syndromes, kidney stones

Underweight BMI

<18.5

Normal BMI

18.5 - 24.9

Overweight BMI

25 - 29.9

Obesity type I BMI

30 - 34.9

Obesity type II BMI

35 - 39.9

Extreme obesity BMI

>40

BMI >25 therapy

Lifestyle modifications

BMI >30 therapy

Pharmacotherapy

BMI > 27 w/ 1 comorbidity or 2 RF’s therapy

Pharmacotherapy

BMI > 40 therapy

Bariatric surgery

BMI >35 w/ 2 comorbidities or 2 RF’s therapy

Bariatric surgery

Obesity Comorbidities

T2DM, Sleep apnea, CVD

Obesity Risk Factors

HTN, Dyslipidemia, impaired fasting glucose, smoking, waist circumference