Experiments

Morgan

showed eye color was carried on x chromosome

Frederick Griffith

• injected mice with ammonia

• showed how two things may be safe by itself but when combined can be fatal

avery mclead and mccarthy

dna is the transforming material

first proof that DNA is responsible for heredity

only DNA treated bottle had no reaction

hershey and chase

demonstrated that DNA not protein is genetic material

used 32p and 35s

chargaff

number of a always equaled number of t

number of g always equaled number of c

Nehlson Stahl

e coli grown with 15N heavier isotype that makes DNA denser

Garrod

isolated homogentistic acid from children

hypothesized tha enxyme for its breakdown was nonfunctional

one gene = one enzyme

Beadle and Tatum

suggested that enzyme knockouts are nonfunctiuonal alleles

one gene = one enzyme

N-crassas was exposed to x rays to cause mutations