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patho final exam
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Structures in Ear
Hear and interpret sounds
Provide info about position and movement of head in space
Receptors within eye
Shapes and colors conveyed in light energy
Impairments to ear and eye
Alter information available to cortex to process
Disease, aging, medications, environmental factors, genetics
Disorders of hearing, balance and vision
Have a negative effect on quality of life
Children will have developmental, communication, and mobility delays
Adults will have mobility, nutrition, stress, coping, and mood problems
increased susceptibility to environmental issues
Hearing process
Sound waves transformed into neural impulses
Pitch, loudness, timing preserved at each step, allowing brain to perceive sound accurately
Auditory system pathologies
Disrupt normal sound transmission process
Types of hearing loss
Sensorineural
▪Conductive
▪Mixed
INNER EAR AND PERIPHERAL BALANCE DO slides 11-13
Conductive Hearing Loss Disorders
Sound unable to travel normally to inner ear
Reflect audibility problem
Types of Conductive hearing loss
Outer ear disorders
Otitis media
Otosclerosis
Outer ear disorders
Highly treatable
Typically do not involve hearing loss
exception is congenital outer ear malformations
Some common disorders
Cerumen impaction
Collapsed ear canal
External otitis
Stenosis of ear canal
Otitis Media (OM)
Inflammation of middle ear space
Associated with Eustachian tube dysfunction
Commonly diagnosed in children
OM Clinical man
Cold like symptoms and/or upper respiratory problems
Acute Otitis Media
Inflammation of middle ear with acute onset
Moderate to severe bulging of TM and middle ear effusion
Complications
Rupture of Tm
Conductive hearing loss (temporary)
Treatment
Antibiotics
Recurrent Acute Otitis Media
3+ episodes of AOM in 6 months
4+ episodes in 12 months
Factors that increase risk
male
Passive exposure to smoking
Winter
Chronic Otitis Media
Infection longer than 6 weeks with persistent effusion in middle ear space
Mild to moderate conductive hearing loss
Treatment:
Topical antibiotics and/or steroids
Frequent cleaning of ear
Severe cases:
Surgery
PE tubes (pressure equalization)
Otosclerosis
Abnormal bone growth in middle ear space
Associated hearing loss
bilateral
Slowly progressive
Conductive
Otosclerosis cause and patho
Alternating bone resorption and formation
Genetic component as autosomal dominant
Viral factors
Autoimmune system disorders
Otosclerosis diagnosis
History
Otoscopy
Audiologic results
Radiologic studies
Otosclerosis treatment
Annual hearing tests
Surgery
Hearing aids
Presbycusis
Hearing loss due to aging
Most common form of hearing loss
Various contributing factors
4 types of Presbycusis
Sensory
Neural
Metabolic/strial
Mechanical/cochlear conductive
Presbycusis clinical man
Progressive decrease in hearing thresholds
Decreased ability to understand speech
Presbycusis diagnosis
History and complete audiologic assessment
Presbycusis treatment
Hearing aids
Assistive listening devices
Cochlear implants
Ménière Disease (inner ear disorder)
Inner ear disorder with both auditory and vestibular symptoms
Excess endolymph within membranous labyrinth of
inner ear
Ménière Disease
Intense vertigo with accompanying nausea and vomiting
Tinnitus
Pressure or fullness in the ear
Fluctuating hearing loss
Ototoxicity
Side effect of some meds
damage to sensory cells of inner ear
Cochleotopic meds
Damage to sensory cells of cochlea
Cause sensorineural hearing loss
Typically bilateral
Vestibulotoxic medications
Damage sensory cells of peripheral balance system
Effects typically bilateral
Factors that affect Ototoxicity
Age
Coexisting medical conditions
Genetic predisposition
Drug
Genetic hearing loss
One of the most common birth defects
Caused by genetic mutation
Genetic hearing loss clinical man
Nonsyndromic hearing loss: Hearing loss only
Syndromic hearing loss: Accompanied by pattern of
other clinical abnormalities
Genetic hearing loss diagnosis
Physical attributes related to syndrome
Genetic testing for definitive diagnosis
Genetic hearing loss treatment
Regular audiologic monitoring
Sensorineural hearing loss
hearing aid or cochlear implant
Conductive hearing loss
hearing aid or osseointegrated hearing implant
Myopia
Nearsightness, image focused in front of the lens
Hyperopia
Farsightness, eyeball is too small, image focused behind the retina
Presbyopia
Farsightness associated with aging, loss elasticity reduce accommodation
Ciliary muscles weakening and th eye’s lens becoming less flexible with age
Astigmatism
Irregular curvature in the cornea or lens
Strabismus
Result from deviation of one eye, double vision (diplopia)
May cause by weak or hypertonic muscle, short muscle or neurological defect
In children - must be treated immediately to prevent development of amblyopia
Nystagmus
Rapid, involuntary eye movement
Develops in some individuals with amblyopia and strabismus.
May result from neurological causes, inner ear or cerebral
disturbance, drug toxicity
Inhered Diplopia
Result from neurological causes (stroke), paralysis of extraocular muscle
Loss depth perception
Color blindness
Types
▪ Red/green color blindness (most common)
▪ Blue/yellow color blindness
▪ Achromatopsia (most severe)
Congenital or acquire
Hordeolum (stye)
Tender, red, often pus-filled bump along edge of eyelid
Bacterial infection in oil glands at base of eyelash
Resolve in week without treatment
Conjunctivitis (pinkeye)
Symptoms
▪Redness, discharge, itching, burning of eyes
▪Increased tearing; blurred vision, Light sensitivity
Viral Conjunctivitis
Most common
Adenoviruses; herpes simplex virus
Resolves 7-21 days
Bacterial Conjunctivitis (chlamydia)
Resolves in 1 week
Symptoms persist up to 3 weeks
Topical antibiotics
Allergic Conjunctivitis
Not contagious
Treated with saline and/or oral and topical meds
Pterygium
Benign growth on Conjunctiva; may extend to cornea
Risk factors:
High levels of UV exposure, wind
Causes for removal
Unsightly
Interferes with vision
Causes discomfort
Keratitis
Severe pain and photophobia: Develops when cornea is infected or irritated
• Transfer from herpes lesion around month.
• Increase the risk of ulceration eroding the cornea.
• Scar formation damages the cornea
Cause: Damage from chemicals, splashes and fume
Corneal Abrasion
Scratch or cut on cornea
Causes:
▪ Foreign body or chemical irritant
▪ Rubbing eye too forcefully or being poked in eye
Symptoms: eye redness, tearing, eye pain, blurred vision, light sensitivity
Treatment
▪ Flushing with water or a sterile saline solution
▪ Topical antibiotics and anti-inflammatories
Cataracts
Cloudy or opaque discoloration of lens
Causes
▪ Age-related changes, trauma, congenital anomalies,
systemic disease, pharmacologic triggers
Diagnosis
▪ Ophthalmologic exam
Treatment
▪ Limit exposure to ultraviolet light
▪ Surgery; ultrasonic vibrations; artificial lens
▪ Capsulotomy
Glaucoma
Increase in intraocular pressure (IOP)
–Leads to slow, painless, progressive loss of vision
–Numerous risk factors
–Cause of blindness
–Signs and symptoms
– Halos around the eye at night
- Loss of peripheral vision.
- Pain may occur if IOP is greatly increased.
Acute Glaucoma (narrow angle)
Angle between cornea and iris is decreased
Cause:
aging developmental abnormalities, trauma or infection
Treatment
Surgery
Chronic Glaucoma (open-angle)
Higher in older than 50
Thickness of trabecular network which allows for resorption of fluid
Pressure increases over time: May cause damage to the retina or optical nerve.
Irreversible and may cause blindness
Retinopathy
Any disorder of, or damage to, retina
exs:
Diabetic retinopathy: Leading cause of blindness in US.
Non proliferative diabetic retinopathy (no- angiogenesis)
Proliferative diabetic retinopathy (PDR) angiogenesis
(angiogenesis)
Retinal Detachment
Retina separates from underlying structures
Risk factors:
significant myopia
Cataract surgery; PDR; trauma
Macular degeneration (age related macular degeneration)
Macula degenerates; distortion or loss of central vision
Dry macular degeneration (most common)
▪Blurry or “wavy” central vision with normal peripheral vision
Wet macular degeneration (more severe)
New blood vessels grow around macula
Causes bleeding, scarring, and photoreceptor atrophy