MCB 170 - Lecture 6

olidendrocytes

myelinating cell type of CNS

What is the effect of myelin on action potential propogation?

saltatory conduction

saltatory conduction

process by which action potentials jump along myelinated axon

myelin

acts as an insulator to prevent chare loss through membrane → faster conduction, decreases membrane capacitance and inc membrane resistance

astrocytes

glial of CNS, important for neurotransmitter clearance at synapses and nutrient/chemical exchange at the BBB

radial astrocytes (tanycytes)

has roles in nutrient sesning, appetite in the hypothalamus, connected to BBB, transition zone b/t PNS ansd CNS

microglia

immune cells of the CNS, roles in synaptic plasticity, neuron growth and development, and immune surveillance

ependymal cels

important for circulation of cerbrospinal fluid (CSF) through CNS

CSF

important for waste removal, maintaining internal pressure, cell signaling

neurovascular unit in CNS

pericytes, endothelial cells

pericytes

critical component of BBB

endothelial cells

make up blood vessels/vascolature

major glial cell in PNS

schwaan cells

schwaan cells

proides support to axons as well some myelin sheath

types of schwaan cells

myelinating or nonmyelinating

nerves

bundles of axons and glial cells in PNS

nerves

tissues, need blood supply

macrophages

immune cells all over body PNS

microglia

immune CNS cells