Ch 8 - Specific Review

Spontaneous reactions

• ΔG must be negative

• exergonic

• ex: catabolic

Non-spontaneous reactions

• ΔG must be positive

• endergonic

• ex: anabolic

Enzyme function

Lower activation energy to speed up metabolic reactions

What effects enzyme activity?

• temperature

• pH

• Inhibitors

Inhibitors

• competitive

• allosteric

• non-competitive

Competitive Inhibitors

binds to the active site

Allosteric Site

• a specific receptor on the enzyme that is NOT the active site

Non-competitive Inhibitors

• bind to the allosteric site

• changes enzyme shape

Cofactors

• help enzymes catalyze reactions