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asymptomatic
absence of any noticeable symptoms, even if lab work or diagnostic tests indicate otherwise
chronic
manifestations or illnesses that occur gradually and generally lasts 6 + months
homeostasis
dynamic, steady state marked by appropriate regulatory responses in the body
morbidity
negative outcome from a disease; poor quality of life from disease
mortality
state of being subject to death; measurement of number of deaths within a specific population in a specific timeframe
nosocomial
illnesses caused by exposure to healthcare environment
pathophysiology
the physiology of altered health status; functional changes that accompany an injury, syndrome, or disease
active transport
energy-dependent transport of particles across the plasma membrane against a gradient
apoptosis
programmed cell death prompted by a genetic signal to rid body of unwanted cells or ones damaged beyond repair; cell suicide
atrophy
decrease in cell size
Differentiation
process of changing the physical and functional properties of a cell to allow greater specificity and functionality to that cell
endocytosis
transport mechanism involving vesicular enclosure of particles from extracellular environment into cytoplasm
exocytosis
movement of granules or particles out of the cell; fusion of membrane surrounding granule with membrane, followed by rupture and release of contents
facilitated diffusion
passive movement of substances across the cell membrane by mean of a protein carrier; not energy dependent
feedback mechanisms
regulatory mechanism; response of input to a system by generation of output in a given system
hydrophilic
affinity to water; water-loving
hydrophobic
lacking affinity to water; hates water
hyperplasia
increase in number of cells
hypertrophy
increase in cell size
metaplasia
changing of one cell to another
osmosis
movement of water across a concentration gradient; water movement from high concentration to low concentration
compliance
expected expandability of lung tissue and chest wall; ease which lungs expand
diffusion
movement of particles from high concentration to low concentration
dysplasia
actual change in cell size, shape, uniformity, arrangement and structure
insidious
gradual in onset
ischemia
local response to decrease in blood supply
osmotic pressure
force generated as water moves through membrane by osmosis
phagocytosis
ingesting large particles such as cells, bacteria, and damaged components
proliferation
rapid generation of new daughter cells from parent cells
syncope
loss of consciousness; fainting
abscess
pocket of purulent exudate
adhesions
fibrous connections between serous cavities and nearby tissues that do not allow surrounding tissues to move freely
autoimmunity
immune responses directed at an individuals own tissues
contractures
areas of shortening or hardening of muscle tissue leading to loss of elasticity and tissue rigidity
debridement
process of mechanically removing debris, including necrotic tissue, from a wound
degranulation
release of chemical mediators in the form of extracellular granules
deniscence
problem of deficient scar formation where the wound splits or bursts open; often a suture line
dyspepsia
vague epigastric discomfort associated with nausea and heartburn
edema
presence of excessive watery fluid that accumulates in tissues; swelling
erythema
redness caused by increased blood flow to the tissues
exudate
watery fluid with a high protein and leukocyte (WBC) concentration that accumulates at the site of injury
hematemesis
vomiting blood from upper GI tract (esophagus, stomach, duodenum)
occult
hidden blood in the stool that is not visible with the naked eye
perfusion
passage of blood or other fluid through a vessel into the vascular bed of a tissue to provide oxygen and other nutrients
permeable
membrane that allows liquids or gases to pass through