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Thermoregulatory response
Getting back to set body temp to maintain homeostasis by undergoing different processes.
Vasoconstriction
Increase body temp (shivering).
Vasodilation
Decrease body temp (sweating).
Core body temperature
A reflection of the balance between heat gain and heat loss by the body to maintain normal core body temp. 97-99.5 degrees. Core body temp is slightly higher than oral, axillary and tympanic.
Hypothalamus
The thermal control center. Receives information from peripheral and central thermoreceptors and compares it with its temperature set point.
Heat loss
Transfer of body core heat to the surface through the circulation. Most body heat is produced by deep core tissues and is lost at the surface of the skin. Metabolism is the main way the body produces heat.
Methods of heat loss
Radiation, conduction, convection, evaporation.
Radiation
Losing heat because the environmental air around us is cooler than our temp.
Conduction
Coming in contact with an item that is cooler.
Convection
Movement of air currents.
Evaporation
Water on skin that gets converted to a water vapor to get rid of heat.
Factors effecting an alteration in core temperature
Conservation of heat (vasoconstriction, shivering, position), heat loss (vasodilation, sweating), metabolism (hormonal increases or decreases).
Methods of obtaining a core temperature
From a rectal thermometer, from the esophagus using a flexible thermometer, from a pulmonary artery catheter that is used for thermodilution measurement of cardiac output, from a urinary catheter with a thermosensor that measures the temperature of urine in the bladder.
Pyrogen
“Fire makers.” Exogenous or endogenous substances that produce fever.
Exogenous pyrogens
Derived from outside the body (bacterial products, bacterial toxins, or whole microorganisms). Induce host cells to produce fever-producing mediators (endogenous pyrogens).
Endogenous pyrogens
Bacteria/products get into blood or tissue, WBC from immune system engulf by-product of bacteria. This releases pyrogenic cytokine, which induces a prostaglandin, which makes hypothalamus move set point, causing fever. Interleukin-1, Interleukin-6, tumor necrosis factor.
Intermittent fever
Temperature returns to normal at least once every 24 hours (spike in temp).
Remittent fever
Temperature does not return to normal and varies in either direction (varies, but not back to normal).
Sustained or continuous fever
Temperature remains above normal with minimal variations.
Recurrent or relapsing fever
There is one or more episodes of fever as long as several days with one or more days of normal temperature between episodes.
Prodrome
Mild headache, fatigue, malaise, fleeting pains.
Chill
Uncomfortable sensation of being chilled, shaking.
Flush
Cutaneous vasodilation, skin warm and flushed.
Defervescence
The initiation of sweating