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Choanal Atresia
Congenital and Hereditary
MOA: Inherited failure of nasal opening
CS: cleft palate, wry face, missing kidneys, Open-mouthed breathing, high aspiration pneumonia risk
ID: nasal fluid test: back flow, rubber tube: cant pass beyond eye level, High BUN/creatinine
Prognosis: poor, surgical correction: balloon dilator, euth 90%
Complete: fatal after birth
Partial: survival 5-8m
semi-obligate nasal breathers
Wry Face
MOA: Inherited, llamas > alpacas
CS: dental issues, eating difficulties
leads to euthanasia
ID: palpation of bony deviation and Xray
TX: dentals 2-3x annually
Blue-Eyed White (BEW)
Alpacas
AKA: Lethal White
MOA: Inherited, All-white with blue eye
two tuxedo grey parents
CS: deaf / does not respond, fail to move w/ herd, welfare issue
ID: genetic test
Ventricular Septal Defect (VSD)
MOA: Congenital or Hereditary
May have normal lifespan: small defect
CS: Stunted growth, poor exercise tolerance, murmur, progresses to heart failure
ID: US, necropsy
Prognosis: good if minimal, fatal if >1 inch (mins after birth)
Patent Ductus Arteriosus (PDA)
MOA: Congenital or Hereditary, failure of closure @ 4d
CS: Continuous "machinery" murmur, bounding pulses, tachycardia, resp distress(severe), pericardial effusion(advanced cases)
ID: Echo, Lg left ventricle enlargement
Left-to-right shunting (most common)
TX: Surgical closure
Prognosis: poor
Polydactyly
MOA: Congenital or Hereditary
3+ claws
Lifespan: 6-8m
CS: develop arthritis, poor mobility
Prognosis: poor, euth due to welfare
Carpus Valgus
MOA: Congenital, trauma, nutrition: Lateral carpus deviation
TX: Early splinting/casting, transphyseal bridging (if growth plate open)
Prognosis: good with early intervention
Female Hereditary Urogenital Defects
Uterus unicornis: Congenital, one uterine horn, leads to dystocia
Double cervices: fail to conceive, leads to dystocia
Segmental aplasia: lead to infertility
Hypospadia
MOA: Urethra opening wrong location, Congenital or Hereditary
CS: Abnormal urination, urine scalding, infections, infertility
TX: Urethroplasty, euth
Hermaphrodites
MOA: Congenital or Hereditary
True: both ovarian + testicular tissue
Pseudo: genital discrepancy (internal vs. external)
CS: Enlarged clit, underdeveloped penis, infertility
ID: hormone testing, US, laparoscopy(identify parts)
TX: gonadectomy
Prognosis: Poor for repro
Primary Immunodeficiency Syndrome in Llamas
MOA: Congenital or Hereditary
CS: chronic sick, poor condition, slow healing, Persistent diarrhea or respiratory illness, poor weight gain, delayed wound healing
ID: Leukopenia, Low IgG/IgM/IgA, Genetic testing
Prognosis: Grave
Berserk Male Syndrome
AKA: Aberrant Behavior Syndrome, Novice Handler Syndrome
MOA: learned behaviors, excessive human bonding
Avoid over handling crias
CS: aggression
Prognosis: Poor often irreversible - Euthanasia
Castration may reduce the risk but not guaranteed
Spitting
MOA: Normal for social hierarchy or defense,
Excessive: stress, fear, poor socialization
TX: Proper socialization, calm environment, remove stressors, training
Obesity
MOA: Overfeeding high quality forage, low activity
CS: Heat stress, Hepatic lipidosis, infertility, dystocia, joint/hoof problems.
TX: Low-quality forage, Avoid grain
Protein-Energy Malnutrition (PEM)
MOA: Inadequate feed, young, pregnant, lactating, cold stress
CS: starving, hepatic lipidosis, poor BCS, dull/brittle hair, patchy alopecia
ID: Feed analysis, look at DDX
TX: : Gradually improve feed quality and quantity
Long term monitoring
Vitimite deficiency
Vit D: Angular limb deformities, rickets, fractures
reduced Ca/P absorption ( Ca:P >1.5:1)
Tx w/ Vit D injections in late autumn and mid-winter
Cu: Rusty color fiber, stringy fiber, lame, anemia
high molybdenum ratio: Ca:Mo 6–10:1
tx w/ injections or feed legumes
Iron: Poor growth, Non-regen microcytic hypochromic anemia.
Parenteral injection (not oral) iron dextran
Se: White muscle dx, acute death, infertity, stillbirths
ID w/ Bld level selenium or glutathione peroxidase
Tx w/ Selenium/vitamin E
Zi: Dry, thick, cracked skin, alopecia on nose bridge
TX w/ supplements and emollients for dry/cracked skin
Ca(hypo): peak lactation, sternal recumbency, low body temperature, C1 atony, bloat.
Tx w/ IV calcium borogluconate
Mg(hypo): lush grass, low quality dry grass hay, recumbency, convulsions w/ stress, grave prognosis
Ph(hypo): decreased bone density, pica, risk of botulism
Tx w/ Sodium phosphate injections
Recumbency
MOA: Colic, tracheal collapse, Hypocalcemia, hypomagnesemia, fatty liver, P. tenuis, trauma, fractures, Endotoxemia
ID: everything
TX: repositioning, soft bedding, ANTI ULCER meds
Risks: aspiration pneumonia, bloating, ulcers
Hyperlipemia
MOA: Neg energy balance: ill, preg, starved
CS: Lethargy, weakness, anorexia, seizures, hepatic lipidosis(fatal)
ID: high triglycerides in blood, milky plasma
TX: fluids, insulin, GI protectants, high energy diets
Prognosis: guarded to poor
Hepatic Lipidosis
MOA: Neg energy balance, Secondary to hyperlipemia
CS: Lethargy, weakness, anorexia, seizures, hepatic encephalopathy
ID: high triglycerides in blood, milky plasma, high liver enzymes (AST, GGT), US, biopsy
TX: fluids, insulin, GI protectants, high energy drenchs
avoid propylene glycol (toxic)
Prognosis: poor
Polioencephalomalacia (PEM)
MOA: Vit B1 Deficiency, disrupted rumen microbiome
CS: Muscle tremors, incoordination, recumbency, opisthotonos, blindness w/ intact PLR
ID: blood levels, UV fluorescence of brain tissue
TX: Thiamine q4 hrs, IV fluids
Prognosis: good if treated early, fatal if delayed
Urolithiasis
Risks: Males, Low Ca:P ratio
MOA: struvite/phosphate stones: High-grain/low-fiber diet
CS: Anuria, teeth grinding, straining, abdominal distension, colic, shock, 48h death
ID: Ultrasound/X-ray.
TX: support, Cystotomy, urethrotomy, urethrostomy, Feed grass hay, ammonium chloride to diet to acidify urine
Prognosis: good if bladders intact, treated early
Liver Abscess
MOA: Secondary to rumenitis, rumen acidosis
CS: chronic/subclinical, weight loss, lethargy, reduced appetite
ID: high WBC + fibrinogen, US
TX: Long term Antibiotics, prevent rumen acidosis(limit grain)
Prognosis: guarded to poor
Pericarditis and epicarditis
MOA: Idiopathic: most common, Secondary to infection
CS: Lethargy, anorexia, fever, muffled heart sounds, tachycardia, weak pulses
ID: echo, rads, pericardiocentesis
TX: NSAIDs, antibiotics, IV fluids, pericardiocentesis
Prognosis: good if not septic
Parelaphostrongylus tenuis (P. tenuis)
AKA: Meningeal worm: deer
MOA: White tail deer, snails/slugs, larvae migrate to spinal cord/brain
CS: Hindlimb weakness, ataxia, circling, head tilt, blindness, seizures, paralysis, recumbency, coma(fatal)
ID: necropsy is definitive - L4/L5 larvae present
CSF high protein w/ mild pleocytosis but NOT specific
TX: tall fences, snail control, monthly ivermectin(high risk) - critical prevention!!
no effective TX
Prognosis: poor once CNS signs
Internal parasites
MOA:
GIT: Haemonchus contortus
Resp: Dictyocaulus viviparus
Fluke: Fasciola hepatica
CS: Anemia, poor growth, rough hair coat, diarrhea
TX: targeted worming(based on worm count), clean pasture p3-4d, selective culling, Ivermectin/Doramectin injection monthly in snail infested areas, monthly fecals, selective culling
Anemia
ID: PCV <12-15%
recheck PCV 3-5 days after event
Regen:
Blood loss: Haemonchus contortus
Hemolysis: Mycoplasma hemolamae, red maple, bracken fern
Non-regen:
Low Copper, Low cobalt, Low iron Chronic dx
TX: transfusion if severe
Cross-match if repeated transfusions
PCV >30% for donor
10-20 mL/kg
Coccidiosis
MOA: Eimeria macusaniensis (llamas, alpacas)
most pathogenic
CS: Severe Diarrhea, weight loss, poor growth, rough hair coat
ID: Fecal smear/flotation, Ulcerated intestines
TX: Amprolium, Sulfas, Ponazuril, Toltrazuril, Decoquinate in feed, cleaning
Foot mites
MOA: Chorioptes
Most common ectoparasite llamas/alpacas!!
Highly contagious
CS: Intense pruritus, alopecia, crusting, scaling
legs, ventrum, tail base
ID: Deep skin scraping
DDX: zinc deficiency, dermatophytosis
TX: Ivermectin, topical acaricides, quarantine
Treat all in-contact animals
Munge
MOA: unknown
CS: dermatitis, hyperkeratotic crusts on the bridge of the nose, periocular, and periaural areas
ID: skin biopsy, skin scraping, culture
DDX: Viral contagious pustular dermatitis, Dermatophilosis, Dermatophytosis, Bacterial dermatitis, Immune-mediated disease, Sarcoptic mange
Rule out zinc: give injection: wont respond
TX: Topical antoparasitic, antibacterial, antifungal, and soothing emollients
some animals do not respond to treatment.
Lice
MOA: Close body contact transmission
Suckling lice: Anemia, debilitation
head, neck and withers.
Biting lice: Feed on skin and hair
base of tail or the side of the neck.
TX: insecticides dusting,
ivermectin (sucking lice only)!
Ticks
MOA: The Rocky Mountain wood tick, hemoplasma
also known as: Mycoplasma hemolamae
CS: tick paralysis
TX: Insecticides dusting, Ivermectin
Heat stress
MOA: Poor ventilation, high ambient temperature and high humidity, obesity.
CS: Depression, dehydration, RR >30, HR >100, drooping lower lip and frothing at the mouth, collapse, >105F
TX: fans, pools, tube w/ cold water, IV cool fluids, shade, low protein diet, ponds, timely shearing
Grave @ temp >108°F.
Enterotoxemias
Type C: Hemorrhagic enteritis - bloody gut
CS: sudden death, bloody diarrhea, blood-stained intestinal contents, abdominal cramps
Type D😩 polpy kidney
CS: Sudden death, convulsions
ID: PCR
TX: IV fluids, Antisera, Antibiotics, Vax
Tetanus
MOA: Clostridium tetani.
wounds, c-section
Blocks inhibitory NT
CS: severe muscle spasms, rigidity, stiff gait, difficulty moving, lockjaw (trismus), hyperresponsiveness, resp failure
TX: Antitoxin, Muscle relaxants (Diazepam, methocarbamol), wound debridement, vax, dark/quite environment
Dental issues
Tooth Root Abscesses
MOA: molars : mandibular > maxillary
CS: Facial swelling, reluctance to eat, purulent drainage
Bone sequestra, osteomyelitis
ID: Oral exam, Rads (#1 gold standard), culture
TX: systemic antibiotics, sxdebridement, tooth extraction
Stomatitis
MOA: oral injuries from grass awns
CS: Ptyalism (drooling), Dysphagia
ID: oral exam
TX: remove FB, mouth wash w/ disinfectant
Megaesophagus
MOA: Segmental dilation of the esophagus.
CS: Postprandial regurgitation, chronic weight loss
ID: Barium contrast rads or fluoroscopy
TX: feed on elevated suface, sm frequent meals
Prognosis: Fair to poor
Acidosis or Grain Poisoning
MOA: Overconsumption/change of grain
CS: Depression, dehydration, left abdominal bloating, ataxia, recumbency, diarrhea after 48hrs, liver abscess(lactic acid), long-term poor performance.
DDX: PEM, salmonella, entertox, preg tox, low Ca, luinosis
TX: fluids, C1 sx, antibiotics, thiamine, quality grass hay, slow diet transition, no grain
NO sweet greens
Prognosis: Poor if down
Stomach Atony
MOA: C1-C2
Grain overload, soiled feed, Prolonged antibiotic therapy, abrupt feed changes
CS: Depression, anorexia, weight loss
DI: Absence of C1 contractions
TX: fluids, transfaunation of C1 fluid
Gastric Ulcers
MOA: compartment 3 and proximal duodenum
Stress
CS: depression, anorexia, colic, bruxism, Melena, recumbency
ID: US
TX: Remove stressors, GI protectants (sucralfate), H2 receptor antagonist (ranitidine, cimetidine, famotidine), PPI (pantopazole or omeprazole)
Regurgitation and Emesis
Regurgitation: Passive process
MOA: FB, megaesophagus, anesthesia/recovery complications
CS: Undigested food
Emesis: Active process
MOA: Severe gastritis
CS: abdominal contractions, partially digested food + bile
Johne's Disease or Paratuberculosis
MOA: Mycobacti avium
CS: chronic PLE, weight loss, ventral edema, intermittent diarrhea
Infection starts early in age, CS appear when old
ID: Fecal culture, Fecal PCR #1, serology after CS
TX: none, remove crias, feed milk replacer, quarantine
Caseous Lymphadenitis
MOA: Corynebacterium pseudotuberculosis
Transmits by direct contact with wounds
CS: Abscesses in retropharyngeal, axillary, popliteal LN
ID: culture abscess, serology
TX: Antibiotics, sx removal of abscesses: not effective test & cull
Diarrhea
Neonatal: Rotavirus, coronavirus, cryptosporidia, E. coli, Abundant dam milk production
virus, bacti, nutrition
Mature: Eimeria spp., Salmonella spp., Mycobacterium paratuberculosis, Intestinal nematodes.
bugs
ID: Fecal cultures, fecal smears, PCR, ELISA, EM.
Fluid Therapy
Route: Oral = mild , IV = Jug, severe, shock, IO = neonates
**Balanced crystalloid: LR, Plasma-Lyte
metabolic acidosis
**NS: metabolic alkalosis
may cause hyperchloremic metabolic acidosis
**Maintain: adults @ 50 or neonates @ 100 mL/kg/day
Replace: BW × % dehydration
**Ongoing: adults @ 25 or neonates @ 50 mL/kg/da
Bicarbonate deficit: X × Body weight (kg) × Base deficit (mEq/L)
X = 0.3 @ adult or 0.6 @ neonate
Assume BD of 10
Add isotonic sodium bicarbonate or hypertonic sodium bicarbonate to NS
TPN/PPN: Anorexic
Neonates use TPN, PPN for adults
Monitor glucose/PCV/TP, electrolytes/acid/base status, Fatty liver
MUST BE administered with fluid pump
Mycoplasma haemolamae
MOA: Ticks
Unique to SACs
CS: Extravascular hemolysis, fever, depression, anemia, icterus, poor growth.
ID: bld smear, PCR, ELISA
TX: Oxytetracycline, transfusions: PCV <15%
If +: Lifelong carriers: cant transmit
Pneumonia
MOA: Pasteurella, Mannheimia, Haemophilus, Mycoplasma, Strep zooepidemicus (alpaca fever) , BHV-1, Adenovirus, coronavirus, aspiration
CS: Depression, anorexia, fever, cough, nasal discharge, tachypnea
ID: Rads, ultrasonography, culture (nasal swab, TTW, BAL)
TX: antibiotics
Prognosis: Good w/ TX
Chronic Obstructive Pulmonary Disease (COPD)
MOA: Chronic lung inflam due to dust, mold, and allergens.
CS: Chronic cough, nasal discharge, labored breathing, exercise intolerance, weight loss.
ID: Rads, BAL, endoscopy
TX: Bronchodilators, corticosteroids, mucolytics, **Improve ventilation, offer low-dust diet **
Ringworm
MOA: Trichophyton verrucosumis: fungal infection
CS: Crusty, circular plaques on head, face, neck, body, and limbs.
ID: Culture, direct microscopic exam of hair or skin scale
TX: self-limiting, iodine topical application
Contagious Ecthyma (Orf)
Sore mouth
MOA: Highly contagious
Zoonotic
CS: Crusty skin lesions on lips, mouth, teats.
ID: PCR
TX: Self-limiting, vaccine
Rabies
MOA: rabid bites
CS: Aggressive or furious, paralytic (dumb), Tenesmus, ptyalism, bloat.
ID: call state vet, histopath, Negri bodies
TX: Killed rabies vaccine, annually
Herpesvirus (EHV-1)
MOA: horses
CS: Fever, lethargy, nasal discharge, cough, conjunctivitis, : most common
acute onset ataxia, hindlimb weakness, recumbency, late-term abortions
Secondary bacterial pneumonia
ID: PCR, Serology (paired samples for rising titers)**
TX: IV fluids, NSAIDs, antibiotics, quarantine 30d, Vax (Equine EHV-1)
West Nile Virus
MOA: Arbovirus (Flaviviridae)
mosquitoes, birds
CS: Fever, lethargy, CNS: hindlimb weakness, ataxia, tremors, recumbency
ID: IgM ELISA, PCR (CSF/tissue)
TX: Vax, mosquito control
Prognosis: Guarded
Eastern Equine Encephalitis (EEE)
MOA: Mosquito
CS: Sudden neurologic deficits, rapid recumbency
Fever: 104 F
ID: IgM ELISA / PCR (post-mortem brain)
TX: none, supportive care, EEE vax, bug control
BVD
MOA: Noncytopathic BVDV 1b: most common
CS: Abortion, stillbirth, premature neonates
PI ciras: death to mucosal dx, stunted growth
ID: PCR, VI
pooled bld for herd testing
TX: vax, cull
identify the PI and cull
Foot & Mouth Disease (FMD)
CS: 104°F fever, anorexia, vesicles on lips, gums, tongue, feet, teats
Aerosol, direct contact
ID: VI, PCR, virus neutralization test for serotyping, ELISA
DDX: Vesicular stomatitis and blue tongue.
TX: Reportable
Tuberculosis (TB)
MOA: Mycobacterium bovis
CS: Chronic weight loss, poor body condition, chronic coughing, enlarged lymph nodes
ID: Tuberculin skin test
TX: Antibiotics long term
Reportable
Poor prognosis
Ulcerative Keratitis
MOA: Trauma, FB, infection
CS: Pain, corneal opacity, vascularization
ID: fluorescein stain, culture, PCR
TX: Triple antibiotic, Atropine ointment, NSAIDs
Prognosis is good
Anterior uveitis
MOA: Infections: Lepto, systemic dz
CS: Miosis(constriction), aqueous flare, hypopyon(pus)
ID: fluorescein stain, culture, PCR, serology
TX: Triple antibiotic, NSAIDs, corticosteroids
Prognosis is guarded: risk of glaucoma
Cataracts
Opacity of the lens leading to vision impairment.
MOA: Congenital, Age
CS: Whitish/gray lens, blindness
TX: Surgical removal
Glaucoma
MOA: Elevated IOP (>30 mmHg), optic nerve damage, 2ndary uveitis, trauma
CS: Tearing, squinting, redness, corneal edema (blue haze), enlargement of the globe, (buphthalmos), blindness.
ID: Tonometry (IOP >30 mmHg)
TX: NSAIDs, SX, Laser ablation of the ciliary body, enucleation if refractory.
prognosis is Guarded
Pinkeye
MOA: summer, fly season, Moraxella spp
CS: Blepharospasm, eye discharge, corneal opacity, ulceration, blindness
ID: Ophthalmic swab for gram stain and culture
TX: antibiotic ointments, NSAIDs, Autogenous vax, fly control
Otitis Externa
MOA: Spinose ear tick, infection
CS: Head shaking, scratching ears, foul odor
ID: Otoscopic exam, cytology, Gram stain, mite check, culture
TX: Chlorhexidine flush (2x daily), broad-spectrum antibiotic and anti-fungal otic ointment
Otitis Media and Interna
MOA: bacti infection
CS: Head tilt, ear droop, flaccid lower lip, collapsed nasal opening with deviation, circling, Facial nerve paralysis
ID: Rads
TX: Antibiotic injections, NSAIDs
Chronic Wasting Disease
MOA: Transmissible prion, deer, elk, moose
Contaminated feed or water
CS: Progressive weight loss, abnormal behavior, tremors, ataxia, difficulty swallowing.
ID: post-mortem histopath of brain
TX: none
poor prognosis
Endometritis
MOA: Primary cause of repro failure, Escherichia coli, Streptococcus zooepidemicus
CS: Repeat breeding, early embryonic death, or abortion, abnormal vag discharge
ID: US, bacti culture.
TX: Uterine lavage w/ warm isotonic saline or antiseptic, Intrauterine antibiotics, Systemic antibiotics, Prostaglandins
moderate repo prognosis
Mastitis
MOA: shortly after parturition
Acute: S. aureus, Strep, E. coli, Klebsiella spp., P. aeruginosa, Trueperella pyogenes
Chronic: high cell counts, Strep. agalactiae and S. aureus
CS: watery or bldy mammary secretions, fever, anorexia, udder swelling, pain
ID: Culture, CMT, SCC
TX: Systemic or intramammary antibiotics, NSAIDs
penicillin, cephalosporins, or amoxicillin
Ulcerative Pododermatitis
MOA: trauma, wet unsanitary conditions
CS: Lameness, swelling, heat in the affected feet, and visible ulcers on the pads
ID: PE, culture
TX: farrier, debride, antibiotics, NSAIDs
Fracture Repair
Types and TX
Comminuted diaphyseal fracture of the humerus
intramedullary pins and multiple cerclage wires
Comminuted mid-diaphyseal metatarsal fracture
compression plate
Comminuted diaphyseal and distal metaphyseal tibial fracture.
transfixation cast
Complications: Implant failure, delayed union, malunion, non-union, osteomyelitis, sequestrum formation
Castration
Why: Cohabitation between males, prevention of unwanted pregnancies, genetic control, reduce aggression
When: 18-24m
Pre OP: fast, Tetanus-toxoid vax, lay recombant, Intratesticular and incisional line blocks
OP:
Scrotal: 2-cm incision lateral of median raphe, left open
Pre-scrotal: 2 cm ventral midline incision just cranial to the scrotal base, close insision
Complications: joint issues
Abdominal Surgery
Left paralumbar fossa
Sternal recumbency
sedation and local anesthesia
Uterus, C1 and spleen
Closure: All muscles are closed in one layer using a simple continuous or interrupted tension-relieving sutures w/ No. 1 PDS or No. 1 polyglactin 910
Right paralumbar fossa
Sternal recumbency
sedation and local anesthesia
C3, liver, small intestine, cecum, spiral colon
Ventral midline
general anesthesia
C3, liver, small intestine, large intestine, bladder, or uterus
Closure of Linea alba: cruciate suture pattern w/ No. 1 polydioxanone or polyglactin 910.
Closure of Skin: subQ suture pattern
Post OP: Antibiotics, NSAIDs, omiprazole
Complications: Incisional infection, hernia, ileus, peritonitis and adhesions.
Colic
CS: Kicking at the abdomen, rolling, and thrashing, restless, Lying with head and neck flat against the ground or down across their back, teeth grinding
dramatic in young, less in adults
ID: PE
Indications for SX: continuous pain, fail to shit >24hrs, fail to piss >6hrs, US w/ distention, hypochloremic hypokalemic metabolic alkalosis, abnormal peritoneal fluid analysis
Cesarean Section
MOA: Fetal malpositioning, poor cervical dilation, Uterine torsion, Schistosoma reflexus
Failure to transition from Stage I to Stage II labor or no progress for 30+ minutes in Stage II labor
Exam: Check for dehydration, shock, fetal evaluation
No SX: Cervix is fully dilated, Pelvis is adequate in size
Needs SX: uterus or fetus are inaccessible, Cervix is closed
Approaches
SX: Left Paralumbar fossa, caudal epidural, sit sternal, line or inverted “L” block
Double layer closure with No. 0 polydioxanone or polyglecaprone
Lavage before replacement
Uterine Torsion
MOA: near term gestation
CS: Abdominal pain, lying down
TX: Rolling, transvaginal manipulation, laparotomy
SX indications: not fixed w/ 2 other attempts, Cervix doesn't dilate, inhibitory fetal factors
SX approach: Left paralumbar fossa laparotomy
Fighting Teeth
Upper and lower canine teeth
Upper third incisors
Mature males
Danger to handers
Not effected by castration
Cut w/ Tooth Saw or OB Wire