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catecholamines
dopamine, norepinephrine, epinephrine
excitatory ionotropic synapses use what neurotransmitter
glutamate
inhibitory ionotropic synapses use what neurotransmitter
GABA
Ionotropic use what neurotransmitters primarily
gaba and glutamate
metabotropic effects
sequence of metabolic reactions that produce slow and long-lasting effects at a synapse, use neuromodulaters
chemicals used by metabotropic synapses
dopamine, norepinephrine, and serotonin, neuropeptides and sometimes glutamate and GABA too
second messenger
a chemical that, when activated by a neurotransmitter, initiates communication to many areas within the neuron
which type of synapse influences activity in much or all of the cell and over a longer time
metabotropic
which type of synapse has effects localized to one point on the membrane
ionotropic
which aspects of behavior are the ionotropic synapses responsible for
vision and hearing
which aspects of behavior are the metabotropic synapses responsible for
taste, smell, pain, arousal, hunger, thirst, emotion, attention
which receptors do hallucinogens attach to
serotonin 2a
which receptors do opiates attach to
endorphins
what does cocaine do
blocks reuptake of dopamine
what do amphetamines do
blocks reuptake of dopamine and other neurotransmitters
why does withdrawal happen from stimulants
after drug wears off presynaptic cell needs time to replenish supply causing lower dopamine levels than usual
how do Cannabinoids work
mimics reverse transmitters leading to decrease the release of both glutamate and GABA
Reuptake
process where neurotransmitters are reabsorbed by the neuron that released them after they've performed their function
Autorecepter
receptors on a presynaptic neuron that provide negative feedback by responding to the transmitter released by that neuron
which is faster electrical or chemical transmission
electrical
when do we use electrical transmission
cases where exact synchrony between cells is important (breathing) (heartbeat)
what is it called with electrical synapse when membrane of one neuron makes direct contact with the membrane of another
gap junction
Hormones
chemical that is secreted by cells in one part of the body and conveyed by the blood to influence other cells
Oxytocin
hormone released by posterior pituitary; important for sexual and parental behavior
Vasopressin
(antidiuretic hormone) hormone released by posterior pituitary; raises blood pressure and enables kidneys to conserve water
Neuroanatomy
the anatomy of the nervous system
central nervous system (CNS)
the brain and the spinal cord
peripheral nervous system (PNS):
nerves outside the brain and spinal cord
somatic nervous system
part of the PNS that consists of the axons conveying messages from the sense organs to the CNS and from the CNS to the muscles
autonomic nervous system
part of the PNS that controls the heart, intestines, and other organs
enteric nervous system
part of the ANS, set of neurons that control digestion
Dorsal
located toward the back
Ventral
toward the stomach
Anterior
Toward the front end
Posterior
Toward the rear end
Superior
Above another part
Inferior
Below another part
Lateral
Toward the side, away from the midline
Medial
Toward the midline, away from the side
Proximal
Located close (approximate) to the point of origin or attachment
Distal
Located more distant from the point of origin or attachment
Ipsilateral
On the same side of the body (e.g., two parts on the left or two on the right)
Contralateral
On the opposite side of the body (one on the left and one on the right)
Coronal plane (or frontal plane)
A plane that shows brain structures as seen from the front
Sagittal plane
A plane that shows brain structures as seen from the side
Horizontal plane (or transverse plane)
A plane that shows brain structures as seen from above
Lamina
A row or layer of cell bodies separated from other cell bodies by a layer of axons and dendrites
Column
A set of cells perpendicular to the surface of the cortex, with similar properties
Tract
A set of axons within the CNS, also known as a projection. If axons extend from cell bodies in structure A to synapses onto B, we say that the fibers "project" from A onto B.
Nerve
A set of axons in the periphery, either from the CNS to a muscle or gland or from a sensory organ to the CNS
Nucleus
A cluster of neuron cell bodies within the CNS
Ganglion
A cluster of neuron cell bodies, usually outside the CNS (as in the sympathetic nervous system)
Gyrus (gyri)
A protuberance on the surface of the brain
Sulcus (sulci)
A fold or groove that separates one gyrus from another
Fissure
A long, deep sulcus
spinal cord
part of the CNS; it communicates with all the sense organs and muscles except those of the head
dorsal root nerves
carry sensory info from body to brain through spinal cord
ventral root nerves
carry motor info to muscles and glands from spinal cord
dorsal root ganglia
clusters of sensory neurons outside the spinal cord
gray matter
areas of the nervous system that are densely packed with cell bodies and dendrites
white matter
area of the nervous system consisting of myelinated axons
how do neurons from gray matter of spinal cord send axons to brain/other parts of cord
through white matter
sympathetic nervous system
a network of nerves that prepare the organs for vigorous activity (fight or flight system)
parasympathetic nervous system
system of nerves that facilitate vegetative, nonemergency responses by the body's organs ("rest and digest" system)
Olfactory
Smell
Optic
Vision
Oculomotor
Control of eye movements; pupil constriction
Trochlear
Control of eye movements
Trigeminal
Skin sensations from most of the face; control of jaw muscles for chewing and swallowing
Abducens
Control of eye movements
Facial
Taste from the anterior two-thirds of the tongue; control of facial expressions, crying, salivation, and dilation of the head's blood vessels
Statoacoustic
Hearing; equilibrium
Glossopharyngeal
Taste and other sensations from throat and posterior one-third of the tongue; control of swallowing, salivation, and throat movements during speech
Vagus
Sensations from neck and thorax; control of throat, esophagus, and larynx; parasympathetic nerves to control stomach, intestines, and other organs
Accessory
Control of neck and shoulder movements
Hypoglossal
Control of muscles of the tongue
medulla oblongata
cranial nerves originating in the medulla control vital reflexes such as breathing, heart rate, vomiting, salivation, coughing, and sneezing
Pons
hindbrain structure that lies anterior and ventral to the medulla
Cerebellum
highly folded hindbrain structure that is important for behaviors that depend on accurate timing
Tectum
roof of the midbrain
superior colliculus
swelling on either side of the tectum; important to visual processing
inferior colliculus
swelling on the surface of the tectum that contributes to hearing
Tegmentum
intermediate level of the midbrain
substantia nigra
a midbrain structure that gives rise to a pathway releasing dopamine
thalamus
main source of input to the cortex
cranial nerves
nerves that control sensations from head, muscle movements in head, and much of parasympathetic output to the organs
Medulla
hindbrain structure located just above spinal cord; could be regarded as enlarged extension of spinal cord
Brainstem
medulla, pons, midbrain, and central structure of the forebrain
parts of hindbrain
pons, medulla, cerebellum
Cerebellum
highly folded hindbrain structure that is important for behaviors that depend on accurate timing
Tectum
roof of the midbrain
superior colliculus
swelling on either side of the tectum; important to visual processing
inferior colliculus
swelling on the surface of the tectum that contributes to hearing
Tegmentum
intermediate level of the midbrain
substantia nigra
a midbrain structure that gives rise to a pathway releasing dopamine
thalamus
main source of input to the cortex
Hypothalamus
control of eating, drinking, temperature control, and reproductive behaviors
Amygdala
temporal lobe structure important for evaluating emotional information especially fear
Basal ganglia
a group of subcortical forebrain structures lateral to the thalamus
nucleus basalis
a forebrain structure that lies on the ventral surface; receives input from the hypothalamus and basal ganglia; sends axons to areas in the cerebral cortex