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Two main cell types in liver
Hepatocytes (liver cells), macrophages (stellate macrophages or kupffer cells)
Functions of the liver
Plasma proteins, bile formation and secretion, metabolism of lipid soluble drugs and steriods, lipoprotein synthesis and secretion, carb metabolism, urea formation
How to identify liver
Dense, collagenous CT capsule, hepatic lobules, and veins
Blood goes through what in the liver
Portal vein, hepatic artery, sinusoids, hepatic sinusoids, bile duct
What does portal vein do
Brings newly absorbed substances from intestines to liver
What do sinusoids do
filter substance through hepatocytes and macrophages
What does hepatic artery do
Brings blood to liver cells, branched off from abdominal aorta
What are hepatic sinusoids
Where portal vein and hepatic artery mix
What is central veins
Where blood from portal vein and hepatic artery collect
Where does blood drain out of liver
hepatic vein
What makes up portal triad
portal vein, hepatic artery, bile duct
What is perisinusoidal space
space between hepatocytes and endothelial cells
What is bile made of
water, bile salts, cholesterol and phospholipids, pigments, electroytes
How is bile made
produced by hepatocytes, collected in bile cancliculi encircling hepatocyte
What is common hepatic duct
drains bile from liver
What is cystic duct
connects common hepatic duct to gall bladder, carries bile in and out
What is common bile duct
fused common hepatic duct and cystic duct, empties bile into dueodenum
What does gallbladder do
stores, concentrates, acidifies, delivers bile to duodenum
Histological appearances of gallbladder
no lamina muscularis mucosae, simple columnar,has serosa and adventitia