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The cell
The simplest collection of matter that can be alive
Cells
Basic structural and functional units of every organism
Prokaryotic cells
Domains Bacteria and Archaea; no nucleus or membrane-bound organelles
Eukaryotic cells
Protists, fungi, plants, and animals; contain nucleus and membrane-bound organelles
Cell membrane
Boundary that encloses all cells
Cytosol
Jellylike substance inside the cell where organelles are suspended
Chromosomes
Structures that contain DNA
Ribosomes
Structures that synthesize proteins
Nucleus
Control center of the cell; contains DNA and mRNA
Nuclear envelope
Double membrane surrounding the nucleus
Nuclear pores
Regulate what enters and leaves the nucleus
Chromatin
DNA + protein complex that makes up chromosomes
Nucleolus
Region where ribosomal subunits are formed
Ribosomes are
Protein synthesis structures made of rRNA and proteins
Free ribosomes
Produce proteins used within the cell
Bound ribosomes
Attached to ER; make proteins for export or membranes
Endomembrane system
Includes nuclear envelope, ER, Golgi, lysosomes, vesicles, vacuoles, and plasma membrane
Vesicles
Membrane sacs used for transport
Endoplasmic reticulum (ER)
Network of membranes involved in protein and lipid synthesis and transport
Rough ER
Has ribosomes; protein synthesis and compartmentalization
Smooth ER
Synthesizes lipids and detoxifies the cell
Golgi apparatus
Modifies, packages, and ships materials in vesicles
Cisternae
Flattened membrane sacs of the Golgi
Cis face
Golgi side that receives vesicles
Trans face
Golgi side that ships vesicles
Lysosomes
Membrane sacs with hydrolytic enzymes for digestion
Lysosome function
Intracellular digestion, recycling materials, apoptosis
Vacuoles
Membrane-bound sacs for storage
Central vacuole
Large plant vacuole that stores water and maintains turgor pressure
Mitochondria
Site of cellular respiration and ATP production
Cristae
Folds of inner mitochondrial membrane that increase surface area
Matrix
Inner fluid-filled compartment of mitochondria
ATP
Short-term energy storage molecule
Chloroplasts
Site of photosynthesis in plants
Thylakoids
Membrane disks where light reactions occur
Grana
Stacks of thylakoids
Stroma
Fluid surrounding thylakoids
Chlorophyll
Pigment that captures light energy
Peroxisomes
Break down fatty acids and detoxify alcohol using H2O2
Cytoskeleton
Network of protein fibers for support, motility, and regulation
Microtubules
Involved in chromosome movement and cell division
Microfilaments
Cell shape, movement, and division
Intermediate filaments
Anchor nucleus and organelles
Centrosome
Microtubule-organizing center
Centrioles
Cylinders involved in cell division
Flagella
Long, few structures that propel cells
Cilia
Short, numerous structures for movement or fluid flow
Cell wall
Rigid layer that protects plant cells and maintains shape
Cellulose
Main component of plant cell walls
Plasmodesmata
Channels connecting plant cells
Extracellular matrix (ECM)
Network outside animal cells made of glycoproteins
ECM function
Strengthens tissues and transmits signals
Tight junctions
Watertight seals between animal cells
Desmosomes
Rivet-like junctions that hold cells together
Gap junctions
Channels allowing ions and small molecules to pass
Prokaryote
No nucleus, DNA in nucleoid, small and simple
Eukaryote
Has nucleus, organelles, larger and more complex
Animal cells
No cell wall, no chloroplasts, store energy as glycogen
Plant cells
Have cell wall, chloroplasts, central vacuole, store starch
Endosymbiont theory
Mitochondria and chloroplasts evolved from engulfed prokaryotes
Endosymbiont evidence
Double membranes, own DNA and ribosomes, independent reproduction
Cell size
Cells must be small to maintain high surface area to volume ratio
Surface area to volume ratio
Affects rate of exchange with environment
Plasma membrane
Selectively permeable barrier
Fluid mosaic model
Membrane is fluid with embedded proteins
Phospholipid bilayer
Double layer of amphipathic phospholipids
Amphipathic
Hydrophilic head and hydrophobic tail
Hydrophobic barrier
Prevents passage of ions and polar molecules
Membrane fluidity
Affected by temperature, unsaturated fats, and cholesterol
Cholesterol
Maintains membrane stability across temperatures
Integral proteins
Embedded in membrane; often transmembrane
Peripheral proteins
Attached to membrane surface
Membrane protein functions
Transport, enzymes, signaling, recognition, adhesion
Carbohydrates on membrane
Cell-cell recognition and communication
Glycoproteins
Proteins with carbohydrate chains
Glycolipids
Lipids with carbohydrate chains
Selective permeability
Membrane allows some substances to cross more easily
Small nonpolar molecules
Cross membrane easily (O2, CO2, N2)
Ions and large polar molecules
Require transport proteins
Passive transport
No ATP required; movement down gradient
Diffusion
Movement from high to low concentration
Osmosis
Diffusion of water
Hypotonic solution
Less solute than cell; water enters cell
Hypertonic solution
More solute than cell; water leaves cell
Isotonic solution
Same solute concentration; no net water movement
Facilitated diffusion
Transport proteins help molecules cross membrane
Channel proteins
Provide hydrophilic passageway
Carrier proteins
Bind and carry molecules across membrane
Aquaporins
Water channel proteins
Active transport
Requires ATP; moves against gradient
Electrogenic pumps
Generate voltage across membrane
Sodium-potassium pump
Pumps Na+ out and K+ into cell
Proton pump
Moves H+ across membrane
Cotransport
Downhill movement of one solute drives uphill transport of another
Bulk transport
Movement of large molecules via vesicles
Endocytosis
Cell takes material in via vesicles
Exocytosis
Vesicles fuse with membrane to release contents
Water potential
Measurement of the amount of free energy in a mole of water; indicates how likely water is to move
Free energy
Energy available to do work or cause movement
What water potential measures
How likely water molecules are to move from one place to another