cns 2 exam 2 drugs

bupropion brand

budeprion, wellbutrin, zyban

bupropion class

NDRI

bupropion uses

major depressive disorder, seasonal affective disorder, smoking cessation

bupropion MOA

inhibits neuronal reuptake of norepinephrine and dopamine

bupropion dose

IR: 100 mg PO TID 12 hr: 150mg PO BID 24 hr: 300 mg PO QAM

bupropion contraindications

seizures, bulimia, anorexia, MAOi use

bupropion BBW

may cause suicidal thoughts in children and young adults

escitalopram brand

lexapro

escitalopram class

SSRI

escitalopram uses

major depressive disorder, generalized anxiety disorder

escitalopram MOA

selectively inhibits serotonin reuptake

escitalopram dose

10 mg PO QD

escitalopram contraindications

none listed

escitalopram BBW

may cause suicidal thoughts in children and young adults

fluoxetine brand

prozac, sarafem

fluoxetine class

SSRI

fluoxetine uses

major depressive disorder, obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder

fluoxetine MOA

selectively inhibits serotonin reuptake

fluoxetine dose

20-80 PO qAM

fluoxetine contraindications

none listed

fluoxetine BBW

may cause suicidal thoughts in children and young adults

sertraline brand

zoloft

sertraline class

SSRI

sertraline uses

major depressive disorder, obsessive-compulsive disorder, panic disorder

sertraline MOA

selectively inhibits serotonin reuptake

sertraline dose

50-200 mg PO QD

sertraline contraindications

disulfiram use

sertraline BBW

may cause suicidal thoughts in children and young adults

venlafaxine brand

effexor

venlafaxine class

SNRI

venlafaxine uses

major depressive disorder, generalized anxiety, panic disorder

venlafaxine MOA

inhibits norepinephrine, serotonin, and dopamine reuptake

venlafaxine dose

IR: 75-225 mg/day PO divided BID-TID ER: 75-225 mg PO QD

venlafaxine contraindications

avoid abrupt withdrawal

venlafaxine BBW

may cause suicidal thoughts in children and young adults

paroxetine brand

paxil

paroxetine class

SSRI

paroxetine uses

major depressive disorder, obsessive-compulsive disorder, panic disorder, social anxiety disorder, generalized anxiety disorder, PTSD

paroxetine MOA

selectively inhibits serotonin reuptake

paroxetine dose

20-50 mg PO qAM

paroxetine contraindications

none listed

paroxetine BBW

may cause suicidal thoughts in children and young adults

desvenlafaxine brand

pristiq

desvenlafaxine class

SNRI

desvenlafaxine use

major depressive disorder

desvenlafaxine MOA

inhibits norepinephrine, serotonin, and dopamine reuptake

desvenlafaxine dose

50 mg PO QD

desvenlafaxine contraindications

avoid abrupt withdrawal

desvenlafaxine BBW

may cause suicidal thoughts in children and young adults

duloxetine brand

cymbalta

duloxetine class

SNRI

duloxetine uses

major depressive disorder, generalized anxiety disorder

duloxetine MOA

inhibits serotonin and norepinephrine reuptake

duloxetine dose

60 mg PO QD

duloxetine contraindications

alcohol abuse, abrupt alcohol withdrawal

duloxetine BBW

may cause suicidal thoughts in children and young adults

citalopram brand

celexa

citalopram class

SSRI

citalopram uses

major depressive disorder

citalopram MOA

selectively inhibits serotonin reuptake

citalopram dose

20-40 mg PO QD

citalopram contraindications

electrolyte abnormalities, QT prolongation, arrhythmias, CHF

citalopram BBW

may cause suicidal thoughts in children and young adults

buspirone brand

buspar

buspirone class

anxiolytic, non-benzodiazepines

buspirone use

anxiety

buspirone MOA

binds to serotonin and D2 receptors

buspirone dose

20-30 PO QD divided BID-TID

buspirone contraindications

MAOi use, renal impairment

buspirone BBW

none listed

mirtazapine brand

remeron

mirtazapine class

antidepressant, tetracyclic

mirtazapine uses

major depressive disorder

mirtazapine MOA

antagonizes alpha-2 adrenergic and serotonin 5-HT2 receptors

mirtazapine dose

15-45mg PO QHS

mirtazapine contraindications

MAOi use, avoid abrupt withdrawal

mirtazapine BBW

may cause suicidal thoughts in children and young adults