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Enzymes
Biological catalysts that speed up chemical reactions
Active site
Region of an enzyme where the substrate binds
Substrate
Molecule that an enzyme acts on
Enzyme–substrate complex
Temporary complex formed when substrate binds to active site
Denaturation
Loss of enzyme shape so substrate no longer fits active site
Optimum temperature
Temperature at which an enzyme works fastest
Optimum pH
pH at which an enzyme works fastest
Catalyst
Substance that speeds up reactions without being used up
What happens to enzyme activity when temperature increases (before optimum)?
Activity increases because particles have more kinetic energy
What happens to enzymes at high temperatures?
They denature
Why does denaturation stop enzyme activity?
Active site changes shape so substrate no longer fits
What happens to enzyme activity at low temperatures?
Reactions are slow due to low kinetic energy
What forms when a substrate binds to an enzyme?
Enzyme–substrate complex
What is the effect of pH on enzymes?
Extreme pH changes denature enzymes
Why are enzymes specific?
Active site shape is complementary to one substrate
What is the optimum temperature for most human enzymes?
Around 37°C
What happens to enzyme activity after the optimum temperature?
It rapidly decreases due to denaturation
What happens to enzyme activity if pH moves away from optimum?
Activity decreases
Why are enzymes important in living organisms?
They allow reactions to occur fast enough to sustain life
What type of molecule are enzymes?
Proteins