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dementia
an acquired global loss of brain function with slow, gradual onset
Alzheimer’s Disease
what is the leading cause of dementia? it causes 60-80% of cases
memory loss plus one additional deficit in an area that affects ADLs
how does one qualify as a dementia patient?
delirium
sudden disturbance in consciousness or change in cognitive ability that fluctuates throughout the course of the day
other medical conditions
what usually causes delirium?
mild cognitive impairment
more severe changes noted than those associated with normal aging, but not severe enough to affect ADLs
decreased ability to concentrate
decreased word-finding abilities
decreased short-term memory
difficulty following detail-heavy conversations
symptoms of mild cognitive impairment
assess and treat cognitive communicative deficits that are a result of dementia
recognize, diagnose, and provide treatment for cognitive, communicative, or swallowing deficits as a result of dementia or dementia-producing illness
what is an SLP’s role with dementia?
language remains intact
sustained attention remains mostly intact
divided attention skills intact during simple tasks
long-term memory and procedural memory remain intact
what areas do not suffer deficits with normal aging (what remains intact)?
slight decline in word-finding abilities
slight decline in selective attention skills
divided attention begins to decline in complex tasks
reaction time is slowed
episodic and short-term memories are reduced
what are some deficits that ARE present in normal aging?
cortical dementias, subcortical dementias, mixed dementias, other considerations
what are some etiologies of dementia?
alzheimer’s
frontotemporal dementia
pick’s disease
kinds of cortical dementias
huntington’s disease
subcortical dementia example
vascular dementia, lewy body disease, progressive supranuclear palsy
kinds of mixed dementias
parkinson’s disease and dementia with lewy bodies
what are the two kinds of lewy body dementias?
drug-induced and depression
what are some other considerations for dementia etiologies?
Alzheimer’s Disease
most common cause of dementia
cortical
progressive and fatal
after age 65
when is the usual onset for Alzheimer’s?
neurofibrillary tangles
amyloid plaques
granulovacuolar degeneration
general neuronal atrophy - shrinking of cortex and widening of ventricles
what does the neuropathology of alzheimer’s include?
clinical signs, autopsy, or Pittsburgh Compound test
how is alzheimer’s diagnosed?
women, family history, history of depression, previous head trauma, education level
risk factors for alzheimer’s disease
early stage
which stage of alzheimer’s is this:
motor function retained
short-term memory loss, word-finding difficulties, comprehension of verbal language deficits, personality changes
lasts about 2 years on average
mid stage
what stage of alzheimer’s is this":
negative impact on ADLs and increased reliance on caregivers
more severe memory loss, attention deficits, dramatic personality changes, visuospatial/visuoconstructive deficits, expressive language deficits
possible wandering, sundowner syndrome, disorientation, confusion
lasts from 4-10 years
avoid messy environments, make sure items are put away neatly and in an organized manner
how can we help with mid-stage alzheimer’s patients experiencing visuospatial and visuoconstructive deficits?
late stage
what stage of alzheimer’s is this:
loss of motor function
memory, cognition, expressive language deficits are profound
muteness or dysphagia
what can profound memory, cognition, and expressive language deficits in late stage alzheimer’s patients cause?
frontotemporal dementia
dementia caused by degeneration of the frontal and temporal lobes
pick’s disease, primary progressive aphasias, progressive nonfluent aphasia, semantic dementia
what does fontotemporal dementia include?
pick’s disease
dementia resulting from progressive degeneration of frontal and temporal lobes
early personality changes, antisocial/inappropriate behavior, memory loss
what is pick’s disease characterized by?
women 50-70 years old
who is usually affected by Pick’s disease?
notable behavioral, emotional, and personality changes without significant language deficits
what differentiates pick’s disease from alzheimer’s disease early on?
frontal lobe degeneration
why does pick’s disease present with such notable behavioral, emotional, and personality changes?
cognitive decline
what can be noted (besides personality changes) with the progression of pick’s disease?
huntington’s disease
subcortical dementia
progressive terminal illness characterized by distinctive involuntary erratic body movements
huntington’s disease
involves degeneration of basal ganglia, hippocampus, substantia nigra, and purkinje of pons
stages one and two
stages of huntington’s disease:
motor symptoms of chorea
emotional problems
difficulty concentrating/memory problems
problems with executive functioning
sleeping/swallowing difficulties
stages two, three, and four
stages of huntington’s disease:
chorea and hyperkinesis that interfere with speech production and swallowing
train on AAC devices
what should huntington’s patients do during stages two, three, and four to prepare for future loss of verbal and written expression?
stage five
stages of huntington’s disease:
nonambulatory
rigidity
bradykinesia
incoordination
total dependence
high risk of aspiration
use of AAC systems
vascular dementia
second leading cause of dementia
vascular dementia
mixed dementia caused by small ischemic strokes within the cortex, subcortex, or both
memory loss, aphasia, apraxia, difficulties with executive functioning
cognitive deficits associated with vascular dementia
lewy body disease
dementia that results in neuropathological changes in the brain due to the presence of lewy bodies in cell body of neurons
Parkinson’s disease
dementia in which patients present with motor abnormalities such as rigidity, tremor, slowness of volitional movement, and cognitive deficits
motor abnormalities at rest, bradykinesia, mask-like facial expressions, difficulty initiating movements for speech, festinations, paresthesia, micrographia
characteristics of parkinson’s
micrographia
small, cramped handwriting
festinations
speeding up repetitive movements (such as shuffling feet while walking)
paresthesia
burning feeling in skin/extremities
dementia with lewy bodies
combination of overall decrease of volitional movement and difficulty initiating motor movement alongside cognitive deficits
significant sleep disturbances and hallucinations/delusions
what are some key characteristics of dementia with lewy bodies?
progressive supranuclear palsy
rare neurodegenerative disorder involving degeneration of the frontal lobe, basal ganglia, and cerebellum
men above the age of 60
who is most affected by progressive supranuclear palsy?
ocular motor problems, personality changes, executive functioning, memory, attention, apathy, impulsivity, balance, dysarthria
issues people with PSP may suffer from
3-5 years
what is the life expectancy for someone with PSP
related causes such as asphyxiation or dysphagia
why do most dementia patients end up passing away?
detailed case history, review of medical chart, interview with family and patient
what should be included in an assessment of dementia?
auditory assessment, motor status, cognitive ability, emotional status, education level, occupation, problem solving ability, living arrangement, impact on safety awareness, reason for referral
what should be included in dementia assessment case history?
toileting, communicating pain level, visiting with family
how could communication affect ADLs?
mini-mental state exam, alzheimer’s disease assessment scale, global deterioration scale, dependence scale, geriatric depression scale
dementia rating scales often used:
slow progression or reduce symptoms
what can medicine do for dementia?
improve quality of life and ensure individual is operating at highest level
reduce demands on impaired abilities
increase use of intact cognitive abilities
caregiver training
provide stimuli that evoke positive emotion and memories
therapy for patients with dementia should…
maximize the potential for participation
when trying to ensure an individual is operating at the highest level possible, we are trying to…
they can all be skilled interventions, but with progressive diseases we can’t just see a patient forever for the same intervention
there are more options early on
things to keep in mind when deciding therapy strategies for dementia
assistive technology
dementia therapy strategy that may use AAC or other non-communication related strategies to assist in ADLs
reminiscence therapy
therapy strategy that uses a semi-cued conversation about past events, experiences, and activities to increase orientation and recall pleasant long-term and episodic memory
cognitive simulation therapy
group therapy for mild-moderate dementia that uses themes, mental stimulation, and activities that improve cognitive function
errorless learning
therapy strategy in which patients are provided with information at a difficulty level within the ability of the patient to maximize patient success and minimize patient failure
spaced retrieval training
therapy strategy: presentation of new or previously known information that must be recalled over increasingly greater intervals of time
memory prostheses
therapy strategy: external memory aids such as memory books/wallets, calendars. smart phones, or personal digital assistance to augment memory
Montessori approach
therapy approach: supports interests and needs by structuting the environment in a certain way and encourages them to remain independent as long as possible
simulated presence therapy
therapy strategy that is aimed to reduce anxiety and challenging behaviors by using audio voice recordings of loved ones
cognitive, visual, auditory
cognitive changes that can be made in therapy
life history videos
therapy strategy that uses custom-made videos that provide audiovisual presentation of personal facts and past events to increase orientation and decrease confusion