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Functions
1. Regulates blood supply
2. Generates blood pressure
3. Routes blood
4. Ensures 1 way blood flow
Heart Characteristics
size of a fist and weighs less than— lb.
Location
between lungs in thoracic cavity
Orientation:
apex (bottom) towards left side
double-layered sac that anchors and protects heart
Pericardium
membrane around heart's cavity
Parietal pericardium
membrane on heart's surface
Visceral pericardium
space around heart
Pericardial cavity
surface of heart (outside)
Epicardium
thick, middle layer composed of cardiac muscle
Myocardium
smooth, inner surface
Endocardium
structures that ensure 1 way blood flow
Valves
between atria and ventricles
Atrioventricular valves (AV)
AV valve between RA and RV
Tricuspid valve
3 cusps
Tricuspid valve
AV valve between LA and LV
Bicuspid valve (mitral)
cone-shaped, muscular pillars
Papillary muscles
In simple terms, papillary muscles are small, finger-like muscles located in the walls of the heart's ventricles (the lower chambers). Their main function is to anchor and control the heart's atrioventricular (AV) valves, specifically the mitral valve and the tricuspid valve. These muscles are connected to the valve flaps by thin strands called chordae tendineae.
When the heart contracts, the papillary muscles contract as well, tightening the chordae tendineae and preventing the AV valves from swinging back into the atria. This helps to ensure that blood flows in the right direction—out of the heart's chambers and into the arteries—rather than back into the atria. Essentially, the papillary muscles play a crucial role in maintaining the proper one-way flow of blood through the heart.
- attached to AV valve flaps
- support valves
Chordae tendinee
Think of chordae tendineae as tiny ropes or strings inside your heart. These "ropes" connect the valves (like the mitral valve and tricuspid valve) to small muscles called papillary muscles in the heart's lower chambers.
When the heart squeezes (contracts) to pump blood, the valves need to close properly to prevent blood from flowing backward. The chordae tendineae help with this. As the heart contracts, these strings tighten and pull on the valves, making sure they stay closed and blood goes in the right direction—out to the body or lungs and not back into the heart's upper chambers.
So, in simple terms, chordae tendineae act like puppet strings, making sure the heart valves close tightly and keep the blood moving where it's supposed to go.
Semilunar valves
base of pulmonary trunk
Pulmonary
base of aorta
Aortic
•1 centrally located nucleus
• Branching cells.
• Rich in mitochondria
Cardiac Muscle
Striated (actin and myosin)
Cardiac Muscle
Ca2+ and ATP used for contractions
Cardiac Muscle
Intercalated disks connect cells
Cardiac Muscle
• Lower portion
• Pumping chambers
Ventricles
• Thick, strong walled
• Contract forcefully to propel blood out of heart
Ventricles
• Contract forcefully to propel blood out of heart
Ventricles
separates right and left ventricles
Interventricular septum
• Upper portion
• Holding chambers
Atria
• Small, thin walled
Atria
• Contract minimally to push blood into ventricles
Atria
separates right and left atria
Interatrial septum
• Blood flows from LA into LV.
Bicuspid Valve: Open?
• Aortic semilunar valve is closed.
Bicuspid Valve: Open?
• Tension on chordae tendinee is low.
Bicuspid Valve: Open?
Bicuspid Valve: Open
This refers to a valve in the heart, specifically between the left atrium (LA) and the left ventricle (LV).
"Open" means the valve is allowing blood to flow from the left atrium to the left ventricle.
Blood flows from LA into LV
This just describes the direction of blood flow. Blood is moving from the left atrium to the left ventricle of the heart.
Aortic semilunar valve is closed
Another valve, called the aortic semilunar valve, is shut. This valve is situated between the left ventricle and the aorta.
"Closed" means that this valve is not allowing blood to move from the left ventricle into the aorta at this moment.
Tension on chordae tendineae is low
There are tiny string-like structures in the heart called chordae tendineae.
"Low tension" means that these structures are not under much stress or tightness at the moment.
In summary, during this specific phase:
The bicuspid valve is open, letting blood move from the left atrium to the left ventricle.
The aortic semilunar valve is closed, preventing blood from leaving the left ventricle and entering the aorta.
The chordae tendineae are not under much tension, meaning they are not tightly stretched.
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Chambers and Blood Vessels • 4 Chambers:
- left atrium (LA)
- right atrium (RA)
- left ventricle (LV)
- right ventricle (RV)
separates atria from ventricles
Coronary sulcus
• plate of connective tissue
• fibrous rings
cardiac skeleton
• surround the atrioventricular and semilunar valves
cardiac skeleton
Right Side of Heart
- carries blood from heart to lungs
- blood is O2 poor, CO, rich
Pulmonary circuit
- receives blood from 3 places: superior and inferior
Right Atrium
drains blood above diaphragm (head, neck, thorax, upper limbs)
Superior vena cava
drains blood below diaphragm (abdominopelvic cavity and lower limbs)
Inferior vena cava:
drains blood from myocardium
coronary sinus
So, your heart has its own blood vessels called coronary arteries that bring this special oxygenated blood to the heart muscle itself. But after the heart muscle uses up the oxygen and other nutrients from the blood, it needs a way to get rid of the "used" blood.
Enter the coronary sinus! It's like a little recycling system inside your heart. The coronary sinus collects the "used" blood from the heart muscle and brings it back to the right side of the heart. From there, the heart pumps it to the lungs, where it gets fresh oxygen again, like taking a big breath of air.
So, in simple terms, the coronary sinus helps your heart get rid of the old, used-up blood and sends it off to get refreshed with oxygen so that your heart can keep pumping and keeping you active and healthy!
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Imagine your heart is like a house, and the rooms inside are the different parts of your heart. Now, every house needs a way to get rid of its dirty water, right? In your heart, the dirty water is actually used blood that needs to go back to the laundry (lungs) to get cleaned up.
Now, the coronary sinus is like the heart's special drain. It's a little pipe that collects all the dirty blood (full of waste and carbon dioxide) from the rooms of the heart, which are like the different parts of the house. The coronary sinus takes this dirty blood and sends it off to the laundry (lungs) where it can get cleaned up and be ready to deliver fresh, clean blood again.
So, the coronary sinus is like the heart's way of keeping things tidy and making sure the blood gets a good cleaning before it goes back to work in the heart again!
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- opens into pulmonary trunk
Right Ventricle
splits into right and left pulmonary arteries
Pulmonary trunk:
carry blood away from heart to lungs
Pulmonary arteries
Blood Flow through Heart
1. RA
2. Tricuspid valve
3. RV
4. Pulmonary semilunar valve
5. Pulmonary trunk
6. Pulmonary arteries
7. Lungs
8. Pulmonary veins
10. Bicuspid valve
11. LV
12. Aortic semilunar valve
13. Aorta
14. Body
4 openings (pulmonary veins) that receive blood from lungs
Left Atrium
- opens into aorta
Left Ventricle
- thicker, contracts more forcefully, higher blood pressure than right ventricle has to get to body
Left Ventricle
carries blood from LV to body
Aorta
- supply blood to heart wall -
originate from base of aorta (above aortic semilunar valve)
Coronary arteries
- has 3 branches
- supply blood to anterior heart wall and left ventricle
Left coronary artery:
Action Potentials in Cardiac Muscle
Changes in membrane channels permeability are responsible for producing action potentials and is called
pacemaker potential.
- Na+ channels open
- Ca2+ channels open
Depolarization phase
- Na+ channels close
- Some K+ channels open
-Ca2+ channels remain open
Plateau phase
- K+ channels are open
-Ca2+ channels close
Repolarization phase
prolongs action potential by keeping Ca2+ channels open.
Plateau phase
take 2 msec, in cardiac muscle they take 200-500 msec.
skeletal muscle action potentials
• contraction of atria and ventricles by cardiac muscle cells
Conduction System of Heart
in RA
where action potential originates - functions
Sinoatrial node (SA node):
functions as pacemaker
- large number of Ca?+ channels
Sinoatrial node (SA node):
Path of Action Potential through Hear
1. SA node
2. AV node (atrioventricular)
3. AV bundle
4. Right and Left Bundle branches
5. Purkinje fiber
produce pressure changes within heart chambers.
Cardiac muscle contractions
re responsible for blood movement.
Pressure changes
Blood moves from areas of high to low" pressure
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contraction of atria
Atrial systole
contraction of ventricle
Ventricular systole
relaxation of atria
Atrial diastole
relaxation of ventricles
Ventricular diastole
Components of ECG/EKG
depolarization of atria
P wave
- depolarization of ventricles
- contains Q, R, S waves
ORS complex
repolarization of ventricles
T wave
First sound (SI)
lubb
second (S2)
dupp
result from opening and closing valves
Sounds
- record of electrical events in heart
Electrocardiogram
- diagnoses cardiac abnormalities
- uses electrodes
Electrocardiogram
- contains P wave, QRS complex, T wave
Electrocardiogram
repetitive pumping action which includes contraction and relaxation
Cardiac Cycle
Cardiac Cycle
• Heart is 2 side by side pumps: right and left
• Atria: primers for pumps
• Ventricles: power pumps
Heart is 2 side by side pumps:
right and left
primers for pumps
Atria
power pumps
Ventricles
repetitive pumping action which includes contraction and relaxation
Cardiac Cycle
• Cardiac muscle contractions produce pressure changes within heart chambers.
• Pressure changes are responsible for blood movement.
• Blood moves from areas of high to low pressure.
true
- volume of blood pumped per ventricle per contraction
- 70 ml/beat
Stroke Volume
heart beats/ min
Heart Rate
volume of blood pumped by a ventricle/ min.
- 5 L/min.
CO = SV x HR
Cardiac Output:
• mechanisms contained within heart
Intrinsic Regulation of Heart
amt. of blood that returns to heart
Venous return
degree ventricular walls are stretched at end of diastole
Preload