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Cannabis definition
Drug derived from Cannabis plant containing THC
Primary psychoactive ingredient cannabis
THC
Non-psychoactive cannabis compound
CBD
Cannabis psychoactive varieties
Marijuana and hashish
Non-psychoactive cannabis uses
Medical CBD treatments
Cannabis inhalation pharmacokinetics
Rapid onset and shorter duration
Cannabis oral pharmacokinetics
Slower onset and longer duration
Why cannabis brownies used
THC dissolves in fat improving absorption
Why THC stays long in body
Stored in body fat
Cannabis pharmacodynamics receptors
CB1 receptors
Endocannabinoid source at synapse
Released from postsynaptic neuron
THC synapse mechanism
Retrograde signaling reduces neurotransmitter release
Why endocannabinoids are neuromodulators
Regulate release of other neurotransmitters rather than directly transmitting signals
Positive cannabis subjective effects
Relaxation and euphoria
Negative cannabis subjective effects
Anxiety and paranoia
Factors influencing cannabis experience
Dose, environment, expectations
Cannabis aggression effects
Does not increase aggression
Cannabis creativity effects
Evidence inconsistent
Cannabis memory effects
Impairs short-term memory
Cannabis attention effects
Reduces attention
Cannabis time perception effects
Slows perception of time
Cannabis IQ effects permanence
Usually not permanent
Cannabis categorization task effects
Impairs complex categorization performance
Cannabis physiological symptoms
Increased heart rate, red eyes, dry mouth
Cannabis medical glaucoma use
Reduces eye pressure
Cannabis medical appetite use
Stimulates appetite
Cannabis medical seizure use
Reduces seizures
Cannabis medical sleep use
Improves sleep onset
Cannabis antiemetic use
Reduces nausea
Cannabis antidepressant use evidence
Mixed and limited
Cannabis muscle spasm treatment
Reduces spasticity
Cannabis pain treatment
Provides pain relief
Best cannabis medical administration method
Not smoking; edibles, oils, or vapor preferred
Cannabis driving effects
Slows reaction time and impairs coordination
Cannabis motivation effects
Evidence inconsistent
Cannabis psychosis risk
Increased risk in vulnerable individuals
Cannabis hormone effects
Alters sex hormones
Cannabis immune effects
Possible immune suppression
Cannabis cancer risk
Evidence unclear
Cannabis dependence severity
Lower than nicotine and alcohol
Cannabis tolerance severity
Mild
Cannabis withdrawal symptoms
Irritability, sleep problems, reduced appetite
Cannabis treatment seeking prevalence
Much lower than nicotine and alcohol