Intracellular compartment and Protein sorting - Week 9
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45 Terms
Organelles in the cell are _______ permeable
Selectively
List the 3 spots where ribosomes are found
Rough ER
Smooth ER
Cytoplasm
The nucleus, ER, and golgi apparatus are examples of Membrane - ______ organelles
closed
The nucleolus and the centrosome are both ______ membrane bound organelles
NOT
Define a cytosolic proteins and where their located
Protein with no sorting signal
Located in the cytosol
Define sorting proteins
proteins that have a sorting signal called a signal sequence
“________ _____” aka sorting signal
Signal sequence
What is the role of signal sequences
directs proteins to the correct compartment at a specific destination in the cell
True or false: each signal is very different
True
True Or False: Proteins are not nuclear encoded
False
What’s the difference between post-translational sorting vs. co-translational sorting
Post: After translation
Co: During translation
Explain how post translational sorting occurs in the cell (1 sentence)
AFTER translation a sorting receptor binds to the protein and transports it to it’s destination
Explain the process of co-translational sorting (1 sentence)
DURING translation the protein’s ER signal attaches to the ER and translation is completed there
Post-translational sorting: Which organelles require proteins to be folded and unfolded
Folded: Nucleus & peroxisomes
Unfolded: Mitochondria & Plastids
Post-translational sorting:
