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What do lectins bind to on pathogen cell surfaces?
Carbohydrates common to pathogen cell surfaces.
What does the lectin receptor CD206 recognize?
Sulfated sugars, polysaccharides with terminal mannose, fucose, or N-acetylglucosamine.
What process is activated by lectin binding?
Phagocytosis.
Which scavenger receptors are found on macrophages?
SR-A and SR-B.
What types of ligands do scavenger receptors bind to?
Negatively charged ligands such as sulfated sugars, lipoteichoic acid, and lipopolysaccharide.
What process is activated by scavenger receptor binding?
Phagocytosis.