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what is cytology
study of cells
how many cells are in the human body?
75 trillion
how many different types of cells are in the human body?
200
what are sex cells?
sperm and egg
what are somatic cells?
everything else
all cells are surrounded by ____ membrane
plasma
plasma membrane ____ cytoplasm
holds in
cytoplasm consists of ____ (fluid) and _____ (structures)
cytosol, organelles
body cells re surrounded by ______ (fluid outside membrane)
interstitial fluid
what is the plasma / cell membrane?
phospholipid bilayer
what are the 4 functions of the cell membrane?
physical barrier, regulates exchange, sensitivity, support
phospholipids _____ into bilayer
self assemble
cholesterol resists _______
osmotic lysis
what are the 4 functions of glycocalyx in the plasma membrane?
protection, anchoring, receptors, identity
what are the most common proteins in the plasma membrane?
integral
what do integral proteins do in the plasma membrane?
span width of membrane
what do peripheral proteins do in the plasma membrane?
stick to inner/outer surface
what do anchoring proteins do in the plasma membrane?
attach
what do recognition proteins do in the plasma membrane?
self identification by immune system
what do enzymes do in the plasma membrane?
start reactions
what do receptors do in the plasma membrane?
signal, import/export
what do carrier proteins do in the plasma membrane?
transport solutes
what do channels do in the plasma membrane?
move ions and H2O in/out
passive transport requires ____ from the cell and relies on ____
no energy, diffusion
active transport requires ____ for the cell to ___ substances
energy, move
diffusion is active or passive?
passive
what is simple diffusion?
movement from high concentration to low
what is the transport mechanism of nonpolar and lipid soluble substances?
simple diffusion
what is facilitated diffusion?
needs transport protein
carriers bind proteins that are ____ or a ____ molecule
large, polar
channels are proteins that act as _____ for water or ions
pores
leak channels are always ____
open
gated channels are ____
regulated
osmosis is the _____ of water through a ______ membrane
diffusion, semipermeable
what is osmotic pressure?
pressure needed to stop water from moving across membrane
isotonic solutions contain solute concentrations ____ to the cell
equal
isotonic solutions have ____ and _____
no net movement, no osmotic pressure
hypotonic solutions contain ___ solutes than the cell
less
hypertonic solutions contain ____ solutes than the cell
more
hypotonic = movement of water ___ cell
into
hypertonic = movement of water ____ cell
out of
active transport requires a _____
transport protein
vesicular transport requires ______ of small molecules or ____ of large particles
bulk transport, absorption
what is exocytosis?
moves out of cell
what is endocytosis?
moves into cell
what does receptor mediated endocytosis do?
takes only what it needs
in receptor mediated endocytosis an endosome is fused with a ______
lysosome
pinocytosis is known as _____
cell drinking
in pinocytosis an endosome is fused with a ______
lysosome
phagocytosis is known as ____
cell eating
in phagocytosis a phagosome is fused with a ______
lysosome
what is microvilli?
ruffles and folds that maximize surface area of membrane
cytoplasm occupies space between _______ and ______
plasma membrane, nuclear membrane
what is cytosol?
fluid
what are inclusions in cytoplasm?
type and number changes with cell
what do organelles do?
carry out cellular functions
what are the 6 membranous organelles?
ER, golgi, lysosomes, peroxisomes, mitochondria, nucleus
what are the 4 non-membranous organelles?
cytoskeleton, centrioles, ribosomes, proteasomes
what does the cytoskeleton do?
organize the cell
how many types of filaments are in cytoskeleton?
4
what are microfilaments made of?
actin protein
microfilament attaches _______ to cytoskeleton
membrane proteins
microfilament controls _____ of cytoplasm
consistency
microfilament produces movement with _____
myosin
what does intermediate filament do? (2 things)
strengthen and stabilize
what is the shape of microtubules and what are they made of?
hollow tubes made of tubulin
where do microtubules come from?
centrosome
what are microtubules?
foundation of cytoskeleton
microtubules assist in _____ and _____
mobility, transport
what do microtubules make up?
spindle apparatus
what does the spindle apparatus do?
nuclear division
what are the 3 organelles in microtubules
centrioles, cilia, flagella
what is thick filament composed of?
myosin protein
thick filament is in ______ only
muscle cells
what does thick filament do?
produce movement with actin
what is a centrosome made up of?
cytoplasm and 2 centrioles
what does a centrosome do? (2 things)
aids in microtubule organization, assembles spindle
cilia is short or long?
short
what do cilia do?
move things over cell
flagellum is long or short?
long
what does flagellum do?
moves cell through environment
what are ribosomes?
site of protein synthesis
ribosomes are 60% ____ and 40% _____
rRNA, protein
what do free ribosomes do?
make proteins for cytoplasm
what do fixed ribosomes do?
attach to ER
what is the endoplasmic reticulum made from?
cisternae
what makes the rough ER rough?
fixed ribosomes
what does the RER do?
make and modify proteins
does the smooth ER have ribosomes?
no
what are the 4 functions of the smooth ER?
lipid metabolism, glycogen and ion storage, detoxification
what is the golgi made up of?
stacks of cisternae
what does the golgi do ? (hint: post office of the cell)
modify and package
what is a lysosome?
temporary digestive organelle
transport vesicles from RER dock on _____ and release contents into golgi
cis face
proteins move between ____ and _____
cis face and trans face
cis face = ____
forming
trans face = ____
maturing
secretory vesicles carry products for use _______
outside cell
membrane renewal vesicles carry products to be put into the _____
plasma membrane
lysosomes contain _____
digestive enzymes