the gram-negative, facultative anaerobic rods

Theodor Escherich

Escherichia is named after a German Austrian pedia and bactenologist named?

Escherichia

-constitute to the major micro flora of the GI tract

- ability to become opportunistic microbes

Eosin Methylene Blue (EMB) agar

Macroscopic appearance of Escherichia coli on —. Note the characteristic metallic, green sheen appearance of the colonies.

peritrichous flagella (H- antigens)

Strains are motile by means of —

capsular polysaccharides (K- antigens)

Invasive strains possess —

Indole, nitrate, and urease

The growth characterstic of E.coli is positive for—

Environment infected with fecal materials

-Carrier animals

Reservoir of E. coli

Feco-oral route

Transmission of E. coli

Enterotoxigenic strains (ETEC)

Commonly observed in neonatal piglets and weanlings

Enterohemorrhagic strains (EHEC)

Associated with edema and entero- toxemia and it involves release of a vaso- toxin

Also known as STEC (Shiga toxin–producing Escherichia coli)

Extra-intestinal pathogenic E. coli (ExPEC)

Refers to E. coli strains that cause disease outside the intestine

Examples: Avian Pathogenic E. coli (APEC), Uropathogenic E. coli (UPEC)

Enteroinvasive strains (EIEC)

Neonates that received inadequate amount of colostrum

Enteropathogenic strains (EPEC)

Diarrhea in animals with attaching and effacing lesions in the intestinal tract

Enteroaggregative strains (EAEC)

Causes occasional diarrhea; minor veterinary importance

Fowl Colibacillosis

Marked by debilitation

Fulminating septicemia

Complicated by respiratory infections (rarely manifested by gastrointestinal symptoms)

Associated with salpingitis, synovitis and panophthalmitis

Poultry

E. coli is rarely implicated in cases of diarrhea

Swine Colibacillosis

Characterized by colonic malabsorption

Neonatal E. coli enteritis, Edema disease, Weanling enteritis

Three distinct manifestations of Swine Colibacillosis

1-4 day- old piglets

Neonatal E. coli enteritis

Edema disease

diarrhea, associated with age, change in feed

occurs shortly after weaning, entero-toxemia cases

Weanling enteritis

Cattle Colibacillosis

Enteric disease (white scours) in calves during the first week of life

Colibacillosis in Lambs

Enteric form occurs in lambs 2-8 days old

Caused by the proliferation of entero-pathogenic, non- invasive strains of E. coli in the upper small intestines

Equine Colibacillosis

Accounts for approximately 1% of abortion cases

Observed in mares and about 25% in infected foals

Canine Colibacillosis

Bacteremia implicated in “fading puppy syndrome”

Term for newborn puppies that seem healthy but fail to thrive and die within the first few weeks, often due to unclear causes

Colibacillosis in Rabbits

Cellulitis accompanied by dysentery and high mortality

o

Somatic

K

Capsular

H

Flagellar

F

Fimbrial antigens

Fecal Samples

Rectal swab and Intestinal contents/scrapings

Sample for collection for enteric diseases

Blood, liver, spleen, kidney, lung, bone marrow, urine, kidney tissue

Sample for collection for extraintestinal diseases

Air sac / perihepatic exudates

Pericardial fluid

Sample for collection for colibacillosis diseases

Apramycin

Chloramphenicol

Spectinomycin

Gentamycin

Trimethoprim-sulfamethoxazole

Ceftiofur

Correction of fluid and

electrolyte imbalance

Treatment for E. coli

Vaccination of gilts and sows with fimbrial K88 antigens

Administration of heat- inactivated bacterins

Good husbandry practices

Prevention and Control of E. coli

Daniel Elmer Salmon

Salmonella is named after an American Veterinarian and pathologist named?

Vi antigen

One capsular type of salmonella

S. gallinarum and S. pullorum

Some Salmonella carry Fimbrae

Salmonella

Aerobic but some are facultative anaerobes

Uses citrate as a carbon source

Produce gas from glucose

Soil, water, vegetation and animal feeds

GI tract of warm and cold-blooded animals

Carrier animals

Reservoir of Salmonella

Feco-oral route

Ingestion

Through the yolk

Horizontal transmission

Argasid ticks (Pullorum and fowl typhoid

Transmission of Salmonella

PHASE I

Colonization of the Intestines

This process is mediated by adhesins

PHASE II

Invasion of the Intestinal Epithelium

Described as an inflammatory response with influx of

polymorphonuclear (PMN) cells

Diarrhea sets in if immune response wanes

PHASE III

Stimulation of Fluid Exsorption

Salmonellosis in Cattle