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Breeding & Genetics & Reproduction
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DNA sequence on the chromosome biological important molecule
Gene
alternative forms of a gene (Bb, bb, BB)
Alleles
all the genetic information or hereditary material possessed by an organism
-genes are ordered sequences
Genome
alleles present at a loci (BB, Bb, bb)
Genotype
the expresses characteristics
-P=G+E (environment)
-color, horned vs. polled, birth wights
Phenotype
▪Primarily determined by genotype
▪Little or no influence on environmental influence
▪Determined/controlled by a # of genes
▪Often detected by the visual observation
▪Examples: hair color, horns
Simply Inhereited Traits
Most traits of economic importance
Affected by many genetics
environment affects gene expression
▪Can measure phenotype, but cannot determine the specific genotype at all genes/ loci affecting phenotype
▪Examples:
•Weights
•Milk production
•Fertility
Performance-ADG, Efficiency, Speed
Polygenetic Traits
Known: effects which have a average effect on all individuals within a specific category
ex age, age of cow and gender
ex weaning weight
calves born earlier in the calving season are older at weaning and will be heavier at weaning
▪Unknown: random in nature
Eviromental Effects on Traits
adjust records to remove environmental affect
Ex:) weaning weight of calves (adj: age of calf, sex) (adj to a common age 205d)
Environmental Adjustment on traits
Mean=the average
Standard Deviation - represents a measure of variation
Normal Distribution
•+ 1 SD = 68% of the population
•+ 2 SD = 95% of the population
•+ 3 SD = 99% of the population
Standard Deviation of populations
Important tool for genetic improvement
Selection
•prevent some from reproducing
•use others to become parents of many offspring▪
Change gene frequency in the population
•increase frequency of desirable genes (alleles)
•decrease frequency of undesirable genes
Selection (part 2)
Differential Reproduction
proper selection of phenotype will change genotype of population over time
Selection is based on..
% of the phenotypic variation that is genetic and transmitted from parents to progeny
Ranges 0-100%
Is a estimate
Heritability
Heritability
selection Differential
Exprected progress from Selection-Factors affecting progress
Differences between the trait mean of the selected animals and the average value for the group which they were selected
Selection Differential
“Phenotype * h²”
ex litter size in pigs: 2(Phenotype # of pigs more than average) × 0.09(heritability of the litter size)=0.18
Breeding value can be estimated by
average age of parents (when offspring born are born)
Generation Interval
1-1.5 years
Generation Interval Average Values-Chickens:
1.5-2 Years
Generation Interval Average Values-Swine:
3-5 years
Generation Interval Average Values-Sheep:
4-6 years
Generation Interval Average Values-Dairy Cattle:
also 4-6 years
Generation Interval Average Values-Beef Cattle:
8-12 years
Generation Interval Average Values-Horses:
Heritability
selection Differential
Generation Interval
Genetic Variation
Affects of Genetic Change Per Year
½ of parents genes are transmitted = ½ breeding value
▪the amount by which the …. Average progeny of the animal is expected to different from the average of the herd or population. the average of the herd or population.
Expected Progeny Difference
good tool for genetic selection
used to compare genetic potential-cattle sheep and swine
base = 0
EPDS
Multiple Trait selection slows change, more desirable
risks-too much progress in one trat may lower productivity in other traits
also traits may be theoretically correlated
some of same genes affect more than one trait
Genetic Change & Selection Methods
Set minimum levels for each trait of importance
relatively common
work with small number of importance traits
Disadvantages-may cull a relatively superior animals for poor performance in a single trait
Methods of Selection—Independent Culling Levels
Recognizes value of multiple traits
economically weights value of different traits
Provides overall ranking from best to worst
Most Effective
Most difficult to develop
Selection Index
Depends on breed association ex: feedlot value, grid value, Beef value.
Selection Index-Cattle Examples
heritable traits
ease of measurements
associated with economic vale
accurate genetic estimates
available genetic variation
Requirements of Effective Selection
Yes, combination-of genetic selection and improved environment
Turkeys: wild- 10lbs in 6 M
Modern- 30lbs in 5M
Does Selection Work?
Genetic Abnormalities
Dwarfism
Tibial Hemimilia
Ectodermal dysplasia
Carcass quantity and yield
DNA Testing-Potential Benefits
Traits without routine performance data (disease resistance, fertility)
Traits that are more evident late in life (cows stays in herd)
Post-selection traits (carcass quantity and palpability) (and yield)
DNA Testing-Benefits
Marbling
environmental factors: time of feed, age, stress, implant system.
Limiting factors for DNA testing
Genomically enhanced EPDs used in most seedstock industries
EPD data
Costs (polygenetic test 20-50 per test)(parent matching 15-25)
DNA Testing- Disadvantages
Breed complementation- match strengths & weaknesses of different breeds
Heterosis (hybrid)-increase in productivity of the crossbred progeny that is greater than expected based on the average of the parents performance.
Why crossbreed?
1.)Terminal-
all progeny are marketed(sold) to produce meat
buy replacement breeding stock
use a performance/ carcass oriented sire breeds
2.)Rotational Crossbreeding(2 or 3 breeds)
crossbred females use to produce new generation
Reproductive heterosis= high (maternal)
Heteroses increases as the # of breeds in cross increase
Crossbreeding Programs
Two breed rotation
females sired by breed A are mated to breed B sires and vice-versa.
Rotational Programs
Science that pertains to the function of organs and organ systems
Physiology and Reproduction
study of the function of the reproductive systems
Reproductive Physiology
Trait of greatist economic importance
Cattle: cost of a open cow
cost of lost calf:1450
maintain:$260-$350
Swine:100-175 a pig
Lost market value for the litter:$400-$700
Horses: Have stud fees from the “champion”
Fertility & Reproductive Rate
They produce quantities of semen
-Sperm cells and Seminal fluids
Find the receptive female
-must have the desire
Mount and serve
-must have to mare and & deliver semen
Reproduction: Males Role
Testicles(2)
-produce sperm cells to fertilize the ovaries
-produce the hormone Testosterone
-masculine appearance & behavior
-stimulates sperm production
-growth
Male Reproductive Organs and Function
Epididymis
-concentration of spermatozoa
-storage of maturation site
Male Reproductive Organs and Function (2)
Scrotum
-Provides support for testicles
-Temp regulation for sperm livability (5-10 below body temp)
Male Reproductive Organs and Function (3)
Section tool used for reproductive management
-used primary in cattle but applicable to all
Good indicator of: age @ puberty/ overall fertility
easy to measure and retable, highly heritable
“the larger the better”
12-14m of age want >32cm
Scrotal Circumference
transportation tube that carries sperm from the epididymis to the urethra
Vas Deferens
larger canal from urinary bladder extending the full length of the penis
Urethra
produce fluids: add volume and nutrients
accessory sex glands
organ of copulation
Penis
engorgement with blood
aids copulation
shuts off bladder flow
erections
develop and release the egg
permit mating(estrus/standing heat)
conception
develop the embryo
nourish the fetus
parturition-birth
Lactation-milk production
Rebreeding
Reproduction: Female's Role
produce the ova(sex cells or eggs)
Female Reproductive Organs and Function-Ovaries
Site of fertilization
transport of eggs to the uterus
Female Reproductive Organs and Function-Oviducts
Site of pregnancy
responsible for expulsion of the fetus (birth)
through muscular contractions
shape of the uterus is species specific
Female Reproductive Organs and Function-Uterus