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Homeostasis
Maintenance of a relatively stable internal environment
Regulated variable
A variable the body controls such as temperature or blood glucose
Internal environment
The extracellular fluid surrounding cells
External environment
Everything outside the body
Four classifications of cells
Muscle, nerve, epithelial, and connective tissue cells
Organization of body systems
Cells to tissues to organs to organ systems to organism
TBW
Total body water in the body
ICF
Fluid inside cells; about two-thirds of TBW
ECF
Fluid outside cells; about one-third of TBW
Plasma
Fluid portion of blood
ISF
Fluid between cells
Negative feedback loop
Control system that returns a variable to its normal range
Importance of homeostasis
Allows cells and organs to function properly
Diabetes
Disorder of impaired blood glucose regulation
Covalent bond
Bond formed by sharing electrons
Polar molecule
Unequal sharing of electrons; hydrophilic
Nonpolar molecule
Equal sharing of electrons; hydrophobic
Four biomolecules
Carbohydrates, lipids, proteins, nucleotides
Carbohydrates
Glucose monomer; stored as glycogen; primary energy source
Lipids
Triglycerides, phospholipids, and steroids
Proteins
Made of amino acids; function as enzymes, structure, transport
Nucleotides
ATP for energy and DNA or RNA for genetic information
Metabolism
All chemical reactions in the body
Anabolism
Energy requiring reactions that build molecules
Catabolism
Energy releasing reactions that break molecules down
1st Law of Thermodynamics
Energy cannot be created or destroyed
2nd Law of Thermodynamics
Energy transformations increase entropy
Endergonic reaction
Requires energy input
Exergonic reaction
Releases energy
Law of Mass Action
Reaction direction depends on reactant and product concentrations
Enzymes
Proteins that lower activation energy
ATP
Primary energy currency of the cell
ATP-CrP system
High intensity, short duration energy system
Glycolysis
Breakdown of glucose to produce ATP
Krebs Cycle
Produces NADH and FADH2 in the mitochondria
Electron Transport Chain
Produces most ATP and requires oxygen
Role of oxygen
Final electron acceptor in the electron transport chain