ANTIPHOSPOLIPID SYNDROME

What is Antiphospholipid syndrome (APS)?

is an autoimmune disorder where the body's immune system mistakenly attacks normal proteins in the blood. This causes the blood to clot too easily, leading to blood clots in veins or arteries

What are Phospholipids?

they help prevent fat buildup in the liver, transport cholesterol out of cells, and form the main structure of cell membranes.

Antiphospholipid syndrome can lead to?

1. Thrombosis

2. Thrombocytopenia

3. Miscarriage

S/S of APS?

1. Deep Vein Thrombosis

2. Stroke

3. Pre-eclampsia

Labs & Diagnostic Test of APS?

1. Lupus anticoagulant test

2. Anticardiolipin antibody test

3. Ultrasound

Medical Management of APS?

ANTICOAGULANTS

1. heparin

Surgical Management of APS?

1. Splenectomy

Why is a splenectomy done?

Splenectomy is done to stop the spleen from destroying too many platelets in APS patients with ITP.

Nursing Dx for APS?

1. INEFFECTIVE PERIPHERAL TISSUE PERFUSION

2. RISK FOR FETAL INJURY RELATED TO IMPAIRED PLACENTAL BLOOD FLOW

3. RISK FOR BLEEDING RELATED TO ANTICOAGULANT THERAPY