Human Responses to Ionizing Radiation

Table

Acute radiation syndrome, Local tissue damage, Hematologic depression, Cytogenetic damage

DETERMINISTIC EFFECTS OF RADIATION ON HUMANS

Hematologic syndrome, Gastrointestinal syndrome, Central nervous system syndrome

Deterministic Effects: Acute radiation syndrome (3)

Skin, Gonads, Extremities

Deterministic Effects: Local tissue damage (3)

Leukemia, Other malignant disease, Local tissue damage, Shortening of life span, Genetic damage

STOCHASTIC EFFECTS OF RADIATION ON HUMANS

Bone cancer, Lung cancer, Thyroid cancer, Breast cancer

STOCHASTIC EFFECTS: Other malignant disease (4)

Skin, Gonads, Eyes

STOCHASTIC EFFECTS: Local tissue damage (3)

Cytogenetic damage, Doubling dose, Genetically significant dose

STOCHASTIC EFFECTS:Genetic damage (3)

Prenatal death, Neonatal death, Congenital malformation, Childhood malignancy, Diminished growth and development

EFFECTS OF FETAL IRRADIATION (5)

deterministic effect

If the radiation response increases in severity with increasing radiation dose, it is called (blank) and occurs within days after the radiation exposure.

stochastic effect

if the incidence of the radiation response increases with increasing radiation dose, it is called a (blank) and is not observed for months or years.

Radiobiology

is the study of the effects of ionizing radiation on biologic tissue.

effects of radiation on humans

The ultimate goal of radiobiologic research is to accurately describe the (blank) so that radiation can be used more safely in diagnosis and more effectively in therapy.