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observational study
Observes individuals and measures variable of interest but does not attempt to influence the response
retrospective study
Researchers first select the subjects and then their past events or existing conditions, to identify potential causes or outcomes of interest
prospective study
observes a group of participants over time to collect data on current exposure and track future outcomes or events
experiment
a scientific procedure undertaken to make a discovery, test a hypothesis,or demonstrate a known fact
Used for cause and effect relationship
treatment
Specific conditions applied to the individuals in an experiment
experimental unit
Smallest collection of individuals to which treatment are applied
subject
When the units are humans
explanatory variable
Helps predict or explain changes in the response variable, manipulated by the researchers
response variable
What is measured at the end of the study
confounding variable
Occurs when two variables are associated in such a way that their effects on a response variable cannot be distinguished from each other
completely randomized design
experimental units are assigned to the treatments completely by chance
comparison, random assignment, control, replication
4 principles of experimental design
comparison
use a design that compares 2 or more treatments
random assignment
Use chance to design experimental units to treatments
Helps create equivalent groups of experimental units by balancing the effects of other variables among the treatment group
control
Keep other variables that might affect the response the same for all groups
Baseline for comparison (how do we know if it worked?)
replication
repeating an experiment or study under the same or similar conditions to test the validity of original findings
placebo
An inactive treatment
placebo effect
favorable response to a fake treatment
statistically significant
An observed effect so large that it would rarely occur by chance
Strong evidence that it was the treatments that caused the difference
block
An experimental design technique that groups similar experimental units into blocks to reduce variability and control the effect of a potential confounding variable
paired design
Each subject receiving both treatments in random order
Create blocks by matching pairs of similar experimental units. Then use chance to decide which member gets the treatment