CHAPTER 26: INTERMEDIATE REACTIONS IN ANAEROBIC GLYCOLYSIS

The process of breaking down glucose into pyruvate in the absence of oxygen, resulting in the production of ATP.

The process of breaking down glucose into pyruvate in the absence of oxygen, resulting in the production of ATP.

Anaerobic glycolysis

A hexose sugar that is cleaved into two triose phosphates during the intermediate reactions of anaerobic glycolysis.

Fructose 1,6-bisphosphate (Frc-1,6-bisP)

An enzyme that catalyzes the conversion of Frc-1,6-bisP into glyceraldehyde 3-phosphate (Gl-3-P) and dihydroxyacetone phosphate (DHAP) during anaerobic glycolysis.

Aldolase

An enzyme that interconverts DHAP and Gl-3-P, with a strong equilibrium favoring Gl-3-P formation during anaerobic glycolysis.

Triosephosphate isomerase

A compound derived from DHAP, which serves as a precursor to glycerol and enters the hepatic gluconeogenic pathway during anaerobic glycolysis.

Glycerol 3-phosphate

An enzyme that catalyzes the transfer of a high-energy phosphate from 1,3-bisphosphoglycerate (1,3-bisPG) to ADP, resulting in the production of ATP during anaerobic glycolysis.

Phosphoglycerate kinase

An enzyme that catalyzes the dehydration of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), generating a high-energy phosphate compound during anaerobic glycolysis.

Enolase

An enzyme that transfers the high-energy phosphate from PEP to ADP, producing ATP and pyruvate during anaerobic glycolysis.

Pyruvate kinase

A process in which a substrate participates in an enzyme-catalyzed reaction that yields ATP, as seen in the reactions catalyzed by phosphoglycerate kinase and pyruvate kinase during anaerobic glycolysis.

Substrate-level phosphorylation