CHAPTER 26: INTERMEDIATE REACTIONS IN ANAEROBIC GLYCOLYSIS

The process of breaking down glucose into pyruvate in the absence of oxygen, resulting in the production of ATP.

Anaerobic glycolysis

A hexose sugar that is cleaved into two triose phosphates during the intermediate reactions of anaerobic glycolysis.

Fructose 1,6-bisphosphate (Frc-1,6-bisP)

An enzyme that catalyzes the conversion of Frc-1,6-bisP into glyceraldehyde 3-phosphate (Gl-3-P) and dihydroxyacetone phosphate (DHAP) during anaerobic glycolysis.

Aldolase

An enzyme that interconverts DHAP and Gl-3-P, with a strong equilibrium favoring Gl-3-P formation during anaerobic glycolysis.

Triosephosphate isomerase

A compound derived from DHAP, which serves as a precursor to glycerol and enters the hepatic gluconeogenic pathway during anaerobic glycolysis.

Glycerol 3-phosphate

An enzyme that catalyzes the transfer of a high-energy phosphate from 1,3-bisphosphoglycerate (1,3-bisPG) to ADP, resulting in the production of ATP during anaerobic glycolysis.

Phosphoglycerate kinase

An enzyme that catalyzes the dehydration of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), generating a high-energy phosphate compound during anaerobic glycolysis.

Enolase

An enzyme that transfers the high-energy phosphate from PEP to ADP, producing ATP and pyruvate during anaerobic glycolysis.

Pyruvate kinase

A process in which a substrate participates in an enzyme-catalyzed reaction that yields ATP, as seen in the reactions catalyzed by phosphoglycerate kinase and pyruvate kinase during anaerobic glycolysis.

Substrate-level phosphorylation