Stem Cells and Cellular Differentiation

totipotent

cell that has ability to produce all differented cells including placenta

pluripotent

any type of cell not including placenta

multipotent

multiple lineages

unipotent

1

when stiff extra cellular matrix occurs what is turned and and what is product

Yap and TAZ turning into bone cell

when soft extra cellular matrix occurs what is turned off and and what is product

Yap and TAz turn into fat cell

4 genes that are highly expressed in pluripotent cells

Oct 4, Sox2, nanog, Lin28

how are stem cells distinguished from other types in the skin

skin stem high in b1 integrins , differentation is keratin 10

pathway of gut epithelium

delta expressed in paneth to notch in stem cells notch turns into absorptive and delta turns into secretory

Common Lymphoid Precursor makes what type of cells?

B and T and NK

Common myeloid breaks down into what two things

granulocyte and megakaryocyte

granulocyte makes what?

macrophage, dedritic cell, neutrophil, esoniphil, basophil, mas cell

mekaryocyte makes what?

erythrocyte and platelets

Hematopoietic Stem cells express what

express Kit, SCA1, and low

CD34

what area has no stem cells

auditory epithelium and retinal epithelium

embryonic stem cells can turn into what

pluripotent

SCNT

reproductive clorning, ethicical issues to be considered, ( dolly the sheep)

IPS Cells

Oct 4, Sox2, KLF4 expressed revert back to pluripotent