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sections
what is nerve centre
types of nerve centres
brain circulation
metabolic factors that affect cerebral blood flow
effects of decreased O2
effects of higher pCo2
cerebrospinal fluid
what is nerve centre
A nerve centre is an area, commonly in either a plexus or ganglion that organise a reflex.
Receptor→ nerve centre→ effector
types of nerve centres
Respiratory centre- nerve centres in the brainstem controlling aspects of respiration
Cardiovascular centre- --accelerator, vasomotor-smooth muscle tone and vessel, cardio- inhibitor- vagus nerve—medulla oblongata
Feeding centre- group of cells in the hypothalamus which when stimulated cause hunger.
Pontine micturition centre → brain stem → relaxes urethral sphincter → micturition
Nerve centre can be found in the brain stem and spinal cord segments
brain circulation
The normal flow of blood within the brain is 50-65 ml of blood/100g of brain tissue/minute.
Cerebral blood flow is related to the metabolic activity of the tissue.
Brain requires glucose
concentrations of what affect cerebral blood flow
Co2 concentration
H+ ion concentration
O2 concentration
effects of decreased O2
Decreased O2 conc. – leads to hypoxia- causes respiratory distress
If blood flow becomes insufficient to supply the brain of the needed amount of oxygen
oxygen deficiency mechanisms cause vasodilation.
Increasing CBF and returning O2 levels to normal.
Low levels have proven to cause coma and diminished neural activity.
effects of higher pCo2
increase in arterial PCo2 increases CBF.
CO2 combines with water in the body fluids to form carbonic acid, → dissociates to form H+ ions
The H+ ions are used for vasodialation of cerebral levels
Vasodilation is needed to remove excess CO2 due to its harmful neural effects.
cerebrospinal fluid
Clear and colourless fluid
Produced by choroid plexus –mainly 3rd ventricle
Choroid plexus produces approx.
500 *-ml of CSF per day.
100-160ml is present at each time
Cushions brain from impact and nutritive, shock absorber
Arachnoid granulations drain CSF
CSF flows throughout the in the brain ventricles and into spinal cord, clearing the metabolic waste from CNS through the blood-brain barrier.
sections
what is reflex
reflex arc is comprised of
types of reflexes
main types of reflex systems
tendon reflexes
withdrawal reflexes
somato-somatic reflex
somato-visceral reflex
viscero-somatic reflex
viscero-visceral reflex
hyporeflexia
hyperreflexia
areflexia
what is reflex
A quick unconscious response from internal or external stimulus- protects/adapts body to change taken place
A reflex arc represents the mechanism of physiological function automatically managed and regulated.
Starts with stimulation of the sensory neurones.
This enables the next neurones to pass on the information to the muscles or glands required.
Some reflexes have a Coordination centre within the brain and spinal cord prior to stimulation of the motor nerve.
The brain modulates reflexes.
There are many sensory inputs which use reflex arcs, including- skin receptors, the retina, muscle sphincter etc
reflex arc is comprised of
Sensory cells, - receptor
Afferent neuron
Synapse
Nerve centre*
Efferent neuron
In some cases Neuromuscular junction → muscle
Effectors- muscle or gland. – reflex action
types of reflexes
Unconditioned-innate- protection
Conditioned - developed from unconditional reflexes
main types of reflex systems
Autonomic reflexes:
Mainly involve internal organs --smooth muscle cells, cardiac muscle cells
inhibit or stimulate the cells and glands.
Somatic reflexes:
Involved in reflex controls of skeletal muscles- voluntary
tendon reflexes
aim to prevent damage occurring , can cause muscles to relax if sensory neurones detect
withdrawal reflexes
part of the autonomic reflexes. E.g. hot object, quick retraction from hot surface.
somato-somatic reflex
plantar reflex
somato-visceral reflex
oculocardial reflex – if pressure applied on eyes, heart rate decreases
viscero-somatic reflex
abdominal wall rigidity
viscero-visceral reflex
pressor reflex---( reflex that constricts arterioles (small blood vessels) and thereby increases the blood pressure.
hyporeflexia
decreased reflex response
hyperreflexia
– exaggerated reflex response
areflexia
absence of reflexes