Pathophysiology of Bacterial Infections: Pneumonia, Urinary Tract Infection and Infective Endocarditis
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18 Terms
pathogen
a disease causing microorganism
infection
a local shift in favor of pathogen over the host w pathological consequences due to toxin production and invasion w subsequent inflammation
virulence
strength of microorganisms’ pathogenicity
virulence factors include
adhesins and protective capsules
adhesins
molecules that mediate pathogen adherence to cell surfaces
inoculum
the quantity of microorganisms the host is exposed to
size of inoculum determines…
the likelihood of infection and may also determine severity.
the minimum of a inoculum varies…
from pathogen to pathogen
microbiome
the totality of microbes, their genetic info, and the environment in which they are normally located and interact
microbiota
the microbial organisms that make up a specific microbiome
dysbiosis
disturbed homeostasis of the microbiota composition in a microbiome
major cause of dysbiosis
antibiotics and other drugs
the relationship of dysbiosis
bi directional
t/f can dysbiosis cause disease
t
t/f cause and effect of dysbiosis is always clear
f - not always
antimicrobial
any substance able to suppress the growth of microorganisms or kill pathogenic microorganisms
antibiotics
a substance produced by one microorganism that selectively inhibits the growth of one microorganism that selectively inhibits the growth of another (usu bacteria)
what infection is the most common infections
bacterial infections
