Quiz 13 Krebs Cycle Set 01

What is the CORRECT order of steps of conversion of pyruvate into acetyl CoA?

decarboxylation, oxidation, transfer to CoA

What condition is essential for conversion of pyruvate into acetyl coenzyme A rather than into lactic acid or ethanol?

aerobic conditions

Identify the anaplerotic reactions of the citric acid cycle (TCA Stage II)

phosphoenol pyruvate → OAA, pyruvate → malate, pyruvate→ OAA

What subunit of the PDH decarboxylates pyruvate?

E1 (pyruvate dehydrogenase)

The formation of FADH2 is seen in the conversion of:

succinate to fumarate in the Krebs cycle.

What enzyme of the TCA cycle is similar to the pyruvate dehydrogenase complex?

a-ketoglutarate dehydrogenase

The conversion of isocitrate to α-ketoglutarate is catalyzed by:

isocitrate dehydrogenase.

Identify the cofactor/cofactors which is/are necessary for the correct functioning of the E1 component of the PDH complex.

thiamine phosphate (TPP)

What subunit of the pyruvate dehydrogenase regenerates the oxidized form of lipoamide?

E3 (dihydrolipoamide dehydrogenase)

In addition to pyruvate dehydrogenase, what other enzyme in the citric acid cycle has a key thiamine pyrophosphate coenzyme?

α-ketoglutarate dehydrogenase