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5 functions of the muscular system
Support the body, allow for movement by making bones and other body parts move, maintain constant body temperature, assist in movement of cardiovascular veins and lymph, protect internal organs and stabilizes joints
2
Perimysium
3
Endomysium
1
Epimysium
Largest to smallest:
Myofibril, muscle fiber, fascicle, actin, myosin, muscle
Muscle, fascicle, muscle fiber, myofibril, myosin, actin
Thin filament
Actin
Thick filament
Myosin
I band
Contains only thin filaments
H zone
Contains only thick filaments
A band
Contains both thin and thick filaments
Z disc
protein disc within I band that anchors thin filaments and connects adjacent myofibrils
A
Z disc
C
I band
D
A band
B
H zone
Step 1 Muscle Contraction
An influx of Ca2+ causes thick myosin filaments to form crossbridges with the thin actin filament by exposing the binding site on actin.
Step 2 Muscle Contraction
The crossbridges change shape as it pulls on filaments which slides towards the center of the sarcomere in the power stroke (the distance between the Z line decreases, shortening the muscle)
Step 3 Muscle Contraction
The crossbridges detach from the actin filament when ATP bonds to myosin head
Step 4 Muscle Contraction
Step 4: The myosin head gets ready to bond to actin again using ATP energy (the cycle is repeated on another site of the actin filament)
What two molecules does actin need to pull on myosin?
ADP and P.
Insertion
Attached to the moveable bone
Origin
It is attached to the immovable (or less moveable) bone
Flexion
Bending movement, that decreases the angle of the joint and bring the articulating bones closer together
Extension
Opposite of flexion, it increases the angle of the joint and brings articulating bones further apart
Rotation
The turning of a bone around its own long axis
Adduction
Moving a part toward the midline
Abduction
Moving a part away from the body
Circumduction
Moving a limb so that it describes a cone in space
Difference between prime mover and antagonist
Prime mover is directly responsible for producing a desired motion, antagonist is a muscle that has action opposite that of prime mover, yields to movement of prime mover.
Difference between PNS and CNS
PNS consists of cranial and spinal nerves, CNS consists of brain and spinal cord.
Difference between sensory and motor divisions of the PNS
Sensory- sends impulses from the senses to CNS. Motor- sends impulses from CNS to muscles and glands
What is cell body of neuron as compared to dendrites and axons?
Cell body contains nucleus, cytoplasm, and organelles. Dendrites and axons are processes. Dendrites brings impulses to cell body, axons send impulses away from cell body.
Astrocytes function
support and anchor neurons to surrounding capillaries
Astrocytes CNS or PNS?
CNS
Microglia function
provide immune response to central nervous system
Microglia CNS or PNS?
CNS
Ependymal cells function
secrete and circulate cerebrospinal fluid
Ependymal cells CNS or PNS?
CNS
Oligodendrocytes function
provide myelin insulation to neurons in the central nervous system
Oligodendrocytes CNS or PNS?
CNS
Satellite cells function
support and anchor neurons in the peripheral nervous system
Satellite cells CNS or PNS?
PNS
Schwann cells function
provide myelin insulation to neurons in the peripheral nervous system
Schwann cells CNS or PNS?
PNS
What are the charges of a resting neuron as compared to its extracellular environment?
Neuron intracellular space is negative, extracellular space positively charged.
Depolarization
Negative membrane potential becomes less negative, reaches zero, then becomes positive.
Depolarization ion coming into neuron
Sodium
Repolarization
Membrane potential is restored to the resting state of -70mV
Repolarization ion coming into neuron
Potassium
How does a cell get back to its resting potential (what pump kicks in)?
The sodium-potassium pump restores ion concentrations to normal.
What is the importance of Ca+2 during release of neurotransmitters?
What are the three layers of meninges from outermost to intermost?
Dura mater (thick, tough layer), arachnoid membrane (thin, cobweb-like layer), pia mater (thin layer containing lots of blood vessels)
Where is CSF produced?
choroid plexuses (in the ventricles)
What is the general path of CSF?
Through the interventricular foramina to the third ventricle, then aqueduct of the midbrain, through the midbrain, into the fourth ventricle. Through median aperture and paired lateral apertures (opening in fourth ventricle), enters subarachnoid space, central canal of spinal cord, subarachnoid space around the surface of brain and spinal cord, reabsorbed through arachnoid granulations into blood.
Gyrus of the cerebrum
ridge in the surface of the cerebrum
Sulcus of the cerebrum
groove in the surface of the cerebrum
Corpus callosum in the cerebrum
a bundle of nerve fibers that connects the two hemispheres of the cerebrum
Cerebral cortex
the most superficial layer of the brain, “gray matter,” made of cell bodies and dendrites
Cerebral medulla
middle layer of the brain, “white matter,” made of myelinated axons
Basal nuclei
deepest layer of the brain, islands of gray matter
Frontal lobe function
voluntary movements, reasoning, decision-making, memory, ability to predict consequences of actions, planning, verbal communication (specifically in Broca’s area)
Parietal lobe function
sensations (pain, temperature, touch), visual-spatial processing, body position
Occipital lobe function
visual processing (vision and memory of objects)
Temporal lobe function
memory, comprehension & pronunciation of words, sensations of smell and sound, emotional association of memories
Thalamus function
relays sensory impulses to the cerebral cortex for processing and sorting
Pineal gland function
Hypothalamus function
responsible for autonomic processes (body temperature, metabolism, blood volume), controls hormones (released by pituitary gland), part of the limbic system which regulates emotions and feelings of pleasure (thirst, hunger, sex, pain)
Midbrain function (part of brainstem)
relays information to cerebrum, controls body movements and posture
Pons function (part of brainstem)
Medulla oblongata function (part of brainstem)
transmits impulses between spinal cord and brain + controls blood pressure, heart rate, coughing, swallowing
Importance of cerebellum
responsible for coordinating movements directed by cerebrum so they are graceful and efficient (involuntary)
How many spinal nerves do you have?
31 pairs
1
Central sulcus
2
Precentral gyrus
3
Occipital lobe
4
Cerebellum
5
Cerebellum
6
Parietal lobe
7
Corpus collosum
8
Thalamus
9
Hypothalamus
1
Olfactory nerve
2
Optic nerve
3
Oculomoter nerve
4
Trochlear nerve
5
Trigeminal nerve
6
Abducens nerve
7
Facial nerve
8
Vestibulocochlear nerve
9
Glossopharyngeal nerve
10
Vagus nerve
11
Accessory nerve
12
Hypoglossal nerve
a
orbicularis oculi
b
zygomaticus
c
depressor anguli oris
d
trapezius
e
pectoralis major
f
serratus anterior
g
rectus abdominis