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Degeneration of motor neurons
What is amyotrophic lateral sclerosis
Lower motor neurons of the anterior horn of the spinal cord and upper motor neurons (betz cells) in the motor cortex
What motor neurons are affected
Muscle atrophy
What is the major symptom of the loss of lower motor neurons
Sporadic or inherited SOD1 gene mutation
What are the main cause of amyotrophic lateral sclerosis
Difficulty with limb movement, esophagus dysfunction, difficulty breathing
What are the main symptoms of amyotrophic lateral sclerosis
Difficultly with limb movement
What si the most common symptom of amyotrophic lateral sclerosis