Lactate Fermentation (10/15)

Daily quiz (EXAM 3)

What frees the thioester-bound intermediate from the active site of GAPDH

Pi (inorganic Phosphate)

enzyme that performs the redox reaction of glycolysis

GAPDH (glyceraldehyde-3-phosphate)

product of PFK1

Fructose-1,6- bisphosphate

enzyme that commits to glycolysis by investing the second ATP

PFK1

What enzyme is responsible for the redox reaction that reduces pyruvate.

LDH

during the GAPDH reaction what amino acid forms a thioester bond to the number one carbon of glyceraldehyde-3-P

Cysteine 

during the GAPDH reaction what is donated to NAD+ to reduce it

Hydride Ion (H-)

What enzyme invests the first ATP to retain glucose within cells

Hexokinase

What is the enzyme that performs the "return on investment" substrate-level phosphorylation in the last step of glycolysis

Pyruvate kinase 

During fermentation, pyruvate is reduced by the compound _____ so as to produce the required oxidized substrate for continuous GAPDH action.

NADH

What enzyme performs the "profit" substrate-level phosphorylation to make ATP

3-Phosphoglycerate kinase

What is the final product of glycolysis

pyruvate

what is the name of the pair of triose-Ps that continue into glycolysis after aldolase cleavage

G3P (glyceraldehyde-3-Phosphate)

What is the low energy product of 3-phosphoglycerate kinase that creates a very negative deltaG reaction

3-phosphoglycerate (3-PG)

What is the donating substrate that produces the "return on investment" ATPs produced at the end of glycolysis

PEP

Lactate goes to the liver to enter _____ to provide more glucose for working muscle.

gluconeogenesis 

What is the substrate that donates a phosphate to make the "profit" ATPs of glycolysis

1,3-bisphosphoglycerate (1,3-BPG)

retained form of glucose within cells

glucose-6-phosphate (Glucose-6-P)