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Vocabulary-style flashcards covering accessory skin structures, skin glands, skin functions, thermoregulation, wound healing, burns, and common hair/nail conditions from the lecture notes.
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Accessory structures of the skin
Originate from the epidermis and extend into the dermis or hypodermis; include hair follicles, nails, and skin glands (sweat and sebaceous).
Hair follicles
Tube-like depression of epidermal cells from which hair develops; extends into the dermis or subcutaneous layer.
Hair root
Part of a hair that extends from the skin surface to the dermis or hypodermis.
Hair bulb
Deepest part of the hair root; contains dividing cells of the hair matrix.
Hair shaft
Part of the hair that extends beyond the skin surface; made of dead epidermal cells.
Hair papilla
Contains blood vessels that nourish the hair.
Hair color
Determined by the type and amount of melanin produced in the hair.
Arrector pili muscle
Muscle attached to the hair follicle; contracts in response to cold or fear, causing goosebumps.
Lunula
Pale half-moon region over the nail matrix; the nail matrix conceals deeper blood vessels.
Nail plate (body)
Visible portion of the nail composed of keratinized cells that overlie the nail bed.
Nail bed
Surface of skin under the nail plate.
Nail matrix
Active growth region at the proximal end of the nail bed; not visible.
Cuticle
Fold at the proximal end of the nail; part of the stratum corneum that extends over the nail.
Nails
Protective coverings on the ends of fingers and toes.
Sebaceous glands
Holocrine glands usually associated with hair follicles; secrete sebum to keep hair and skin soft and waterproof; excess sebum can cause acne; absent on palms and soles.
Sebum
Fatty secretion with cellular debris produced by sebaceous glands; keeps hair/skin soft and waterproof.
Acne vulgaris
Disorder of sebaceous glands common at puberty; glands overreact to androgens; clogged glands with sebum and epithelial cells; infection and inflammation; treated with Vitamin A derivatives, systemic antibiotics, salicylic acid, benzoyl peroxide.
Eccrine (merocrine) sweat glands
Most numerous; secretion mainly water, salts, and wastes; regulate body temperature; open to the skin surface through pores.
Apocrine sweat glands
Less numerous; open into hair follicles in axillary and groin areas; secrete by exocytosis; respond to emotions and pain.
Ceruminous glands
Modified sweat glands that secrete ear wax; located in the external acoustic meatus.
Mammary glands
Modified sweat glands that secrete milk; located in the breasts.
Skin functions
Protective barrier; sensation; excretion; production of Vitamin D; regulation of body temperature.
Vitamin D production
Starts in the skin and, when activated, helps with calcium absorption.
Regulation of body temperature
Skin contributes to cooling via sweating and adjusting blood flow.
Heat production
Heat is produced by cellular metabolism, mainly in active cells of the liver and skeletal/cardiac muscle.
Heat loss mechanisms
Radiation (primary), conduction, convection, and evaporation.
Set point
Target body temperature monitored by the hypothalamus (about 37 C / 98.6 F).
Hypothalamus
Brain region that monitors temperature and initiates responses to regulate it.
Thermoreceptors
Receptors that signal the hypothalamus about temperature changes.
Vasodilation
Dilation of dermal blood vessels to release heat.
Vasoconstriction
Contraction of dermal blood vessels to conserve heat.
Hyperthermia
Abnormally high body temperature; can occur when heat loss is overwhelmed by heat input; skin may become dry and the person weak or dizzy.
Fever
Elevated body temperature due to immune response; hypothalamic set point raised by pyrogens to help combat pathogens.
Pyrogens
Substances that raise the hypothalamic set point during fever.
Hypothermia
Abnormally low body temperature from cold exposure or illness; shivering; can progress to confusion and loss of reflexes.
Inflammation
Normal response to injury; blood vessels dilate and become more permeable; redness, swelling, warmth, and pain may occur.
Clot
A fibrin-based network with blood cells and platelets that seals a deep cut.
Scab
Dried clot and tissue fluid that forms over a wound to protect it while healing proceeds.
Fibroblasts
Cells that secrete collagen to bind wound tissue and aid healing.
Growth factors
Signals that stimulate new tissue formation during healing.
Phagocytic cells
Cells that remove dead cells and debris during wound healing.
Scar
Elevated mass of collagen fibers formed during healing; may result from excess scar tissue.
Burns
Injuries classified by depth: superficial/first-degree; deep partial-thickness/second-degree; full-thickness/third-degree.
First-degree burn
Superficial burn affecting only the epidermis; redness and inflammation; heals in days to weeks; no scarring.
Second-degree burn
Deep partial-thickness burn destroying epidermis and part of dermis; may blister; regeneration depends on stem cell survival; hair follicles and glands can aid regeneration; usually no scarring.
Third-degree burn
Full-thickness burn destroying epidermis, dermis, and accessory structures; often requires grafting; limited healing from margins.
Rule of Nines
Estimate burn extent by dividing the body into regions near 9% each to guide treatment.
Androgenic alopecia
Pattern baldness; hair loss at the top of the head linked to androgens and testosterone/estrogen balance.
Alopecia areata
Autoimmune hair loss where antibodies attack hair follicles.