prototype drugs unit 3 pt 2

atorvastatin

HMG-CoA reductase inhibitors

simvastatin

HMG-CoA reductase inhibitors

cholestyramine

bile acid sequestrant

colesevelam

bile acid sequestrant

gemfibrozil

fibric acid derivative

ezetimibe

cholesterol absorption inhibitor

aspirin

platelet aggregation inhibitors

clopidogrel

platelet aggregation inhibitors

nitroglycerin (tablet SL)

short acting vasodilator

isosorbide mononitrate

long acting vasodilator

nitroglycerin transdermal patch

topical vasodilator

warfarin

anticoagulant (coumarin derivative)

heparin

anticoagulant

enoxaparin

low molecular weight heparin (LMWH)

vitamin K

reversal agent of warfarin

protamine sulfate

reversal agent of heparin and enoxaparin

alteplase

fibrinolytics/thrombolytics

digoxin

cardiac glycoside (affecting myocardial contractility)

propanolol

beta blocker

metoprolol

beta blocker

amiodarone

potassium channel blocker

verapamil

calcium channel blocker

diltiazem

calcium channel blocker

adenosine

medication to treat very high HR

ace inhibitors/ARBs

what class is the 1st line of afterload reduction?

-statin

HMG-CoA reductase inhibitor suffix

Internalized Normal Ratio (INR) and Prothrombin time (Pt)

labs for warfarin

Partial Thromboplastin Time (PTT)

lab for heparin

1

INR normal value

2-3.5

INR therapeutic range

3.5-5 mEq/ml

therapeutic serum K level

BUN, creatinine (Cr)

renal function labs

digoxin immune fab (Digibind)

digoxin overdose antidote

s/s of toxicity or HR <60bpm

when would you hold a dose of digoxin?

therapeutic digoxin level

0.5 - 2ng/ml