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Vitamins
Do not provide energy, but are needed for growth, reproduction, and overall good health . They are Classified as either fat-soluble or water-soluble
Fat-soluble vitamins
A,D,E,K
Water-Soluble Vitamins
B,C
Absorption of fat-soluble vitamins
Packaged in fatty acids and bile in micelles, micelles carry it into the intestinal wall, absorbed through wall and packed into chylomicrons, enter lymphatic system then circulatory system
Absorption of water-soluble vitamins
Enter directly into the bloodstream through the intestinal walls
Fat-soluble vitamins are stored and used when
Dietary intake falls short
Liver mainly stores
Vitamin K and E
Vitamin D is mainly stored in
Muscle and fat tissue
For water soluble vitamin storage
Excess is not stored, but excreted in urine
Oxidation is a
harmful chemical reaction that takes place in your cells in which oxygen combines with other molecules
Oxidation results in free radicals, which are
unstable oxygen containing molecules that can damage the cell structure, cell proteins, or even DNA
Antioxidants
harness the free radicals and neutralize them so they stop damaging cells
Oxidants
Substances that promote oxidation
Foods high in antioxidants also tend to contain
Phytochemicals
When free radicals accumulate faster than your body can neutralize them the effects can contribute to
Heart disease, Cancer, Arthritis, Diabetes, Macular Degeneration, Parkinson’s Disease, Alzheimer’s Disease
Oxidative stress and eye health
Age-related Macular Degeneration (AMD) and Cataracts
Age-related Macular Degeneration (AMD) is
More common among those 50+ years old and is the leading cause of vision loss among older adults
Cataract
Disorder in which lens of eye becomes cloudy resulting in blurred vision
Age-related Macular Degeneration (AMD) results from
Damage to the macula
More than half of Americans have cataracts by
80 years old
Bioavailability
The degree to which a nutrient absorbed from foods is used in the body
Bioavailability varies across vitamins based on
Amount of the vitamin in the food
If the food is raw, cooked, or refined
How efficiently the food is digested andabsorbed
Individual’s nutrition status
If the vitamin is natural or synthetic(produced in a lab)
If the body needs more vitamins
It will absorb more vitamins (i.e. young child or pregnant women)
Water-soluble vitamins can be destroyed by
Exposure to air, water, or heat
Fat soluble vitamins are more stable but
Some preparation techniques can cause loss of those vitamins
Fruits and vegetables begin losing vitamins
As soon as they’re harvested
Tips for maintaining vitamins in foods
Don’t expose produce to air
Use less water for cooking
Reduce cooking time
Keep food cold
Hypervitaminosis
Vitamin toxicity
Fortified foods can provide
additional nutrients for those falling short on needs but should not displace vitamin/mineral-rich foods
Fortified foods
Foods that have nutrients added to them
Minerals are
Indestructible
Preformed vitamins
Are already in their active form in the foods you consume
Provitamins
Substances found in foods that can be converted into an active vitamin once they are absorbed
Provitamin example
Beta-carotene is split into 2 molecules of Vitamin A in the small intestine or liver
Vitamin A
Family of substances called retinoids (retinol, retinal, retinoicacid)
Vitamin A is only found in
Animal Sources
Vitamin A is a preformed vitamin
because they are in a form your body readily uses
Plant sources contain provitamin A carotenoids
Which can be converted into retinol in your body
What three carotenoids can be converted into Vitamin A?
Beta-carotene
Beta-cryptoxanthin
Alpha-carotene
Vitamin A functions
Eye health, cell differentiation, cell division
Light sensitive proteins vitamin A makes
Rhodopsin and Iodopsin
Rhodopsin
Needed for night vision
Lodopsin
Needed for color vision
Cell differentiation
Process that determines what a cell becomes in your body
Vitamin A impacts
Cell division by prompting gene expression
Food sources of vitamin A
organ meats (liver), milk, eggs, carrots, spinach, sweet potatoes, pumpkin
Overconsumption of vitamin A can cause
carotenoderma
Orange tinted skin
Underconsumption of vitamin A can lead to
Night blindness, Xerophthalmia, Permanent damage to the cornea, Main cause of preventable blindness in children, Stunted bone growth
Vitamin E
8 different forms, but alpha-tocopherol is most active form in body
Vitamin E functions
Acts as a powerful antioxidant and anticoagulant
Vitamin E food sources
Vegetable oils, nuts, seeds, fortified cereals, some green leafy vegetables
Overconsumption of synthetic form in dietary supplements and fortified foods can increase
Risk of a hemorrhage (Excessive loss of blood or bleeding)
Upper limit of vitamin E
1,000 milligrams/day
Underconsumption of vitamin E can cause
Nerve problems, muscle weakness, and free radical damage to cell membranes
Vitamin K
Menaquinone and Phylloquinone
Vitamin K functions
Essential for blood clotting (coagulation)
Enables bone protein osteocalcin to bind with bone-strengthening mineral, calcium
Vitamin K food sources
green vegetables such as broccoli, asparagus, spinach, salad greens, brussels sprouts, cabbage
also vegetable oils and margarine
Underconsumption of Vitamin K
Problems with blood clotting (very rare)
Vitamin D
Called "sunshine vitamin" because it is made in the body with the help of sunlight (Ultraviolet (UV) rays)
Vitamin D functions
Active form acts as a hormone to regulate calcium and phosphorus
Stimulates intestinal absorption of calcium and phosphorus to maintain healthy blood levels and build and maintain bones
If dietary calcium is too low
Vitamin D and parathyroid hormone signal calcium to leave bones in order to maintain healthy blood calcium levels and Vit D signals kidneys to decrease calcium excretion in urine
Food sources Vitamin D
Fortified milk and yogurt, fortified cereals, fatty fish (e.g., sardines, salmon)
Underconsumption of vitamin D
Rickets: Bones inadequately mineralized with calcium and phosphorus, causing them to weaken and leading to bowed legs
Osteomalacia: adult equivalent of rickets
There are 9
Water soluble vitamins
Thiamin B1 functions
Transmission of nerve impulses
Metabolism of carbohydrates and certain amino acids
Plays role in breakdown of alcohol in body
Thiamin B1 Food sources
Enriched and whole-grain products, pork
Thiamin B1 underconsumption
beriberi: thiamin deficiency disease
Symptoms can include rapid heartbeat, edema, confusion, loss of coordination
Riboflavin (B2)
Light-sensitive vitamin abundant in milk
Riboflavin (B2) functions
Important for energy metabolism (helps turn carbs, fats, and proteins into energy)
Keeps cells healthy
Enhances functions of other B vitamins, such as niacin and B12
Riboflavin (B2) food sources
Milk, yogurt, enriched cereals, grains
Riboflavin (B2) Underconsumption
Sore throat, swelling inside mouth, inflamed and purplish-red tongue (glossitis), dry and scaly lips
Niacin B3
Energy metabolism
Synthesize fat and cholesterol
Keep skin cells and digestive system healthy
Can reduce “bad” cholesterol and raise “good cholesterol”
Niacin B3 food sources
Meat, fish, poultry, enriched whole-grain breads, fortified cereals
Niacin B3 overconsumption
Can cause flushing (reddish coloring of the face,arms, and chest)
Nausea and vomiting
Can be toxic to liver
Can raise blood glucose levels
Niacin B3 underconsumption
Pellagra: niacin deficiency disease
Four Ds: dermatitis, diarrhea, dementia, death
Vitamin B6 functions
Make nonessential amino acids
Convert tryptophan to niacin
Ids in hemoglobin synthesis in red blood cells
Keeps immune and nervous systems healthy
Metabolize fats and carbohydrates and break down glycogen
Vitamin B6 food sources
Meat, fish, poultry, fortified cereals, nuts, legumes, peanut butter, many fruits and vegetables
Vitamin B6 overconsumption can cause
Nerve damage, loss of control of bodily movements, gastrointestinal issues
Vitamin B6 underconsumption
Sore tongue, skin inflammation, depression, confusion, anemia
Alcohol use disorder can cause body to lose B6and may result in deficiency
Folate B9 functions
Vital for DNA synthesis
To create and maintain new cells, including red blood cells
To help body use amino acids
May help fight cancer
Helps with growth and development of embryo in early pregnancy
Folate
Naturally occurring form in foods
Folic Acid
Synthetic form of folate added tofoods and supplements
Folate B9 food sources
Enriched grains (rice, pasta, breads, cereals),legumes, broccoli, asparagus, leafy greens such as spinach
Underconsumption of folate B9
During pregnancy – can result in neural tube defects (Spina bifida or anencephaly)
Macrocytic anemia – form of anemia characterized by large, immature red blood cells with diminished oxygen-carrying capacity
Vitamin B12/ Cobalamine is the
Only water-soluble vitamin that can be stored in your body (liver)
Vitamin B12 functions
To make DNA, To use certain fatty acids and amino acids, For healthy nerves and cells, especially red blood cells
Ability to absorb naturally occurring B12
Declines with age
Vitamin B12 food sources
Animal foods (meat, fish, dairy, poultry)
Synthetic found in fortified foods like soymilk and some cereals
Vitamin B12 underconsumption
Can cause macrocytic anemia (same as folate deficiency)
Can result in pernicious anemia and a need for B12 injections directly into bloodstream to bypass intestine
Pantothenic Acid (B5) and Biotin (B7)
Type of B vitamins
Pantothenic Acid (B5) and Biotin (B7) functions
Assist in energy metabolism of carbohydrates, fats, protein
Pantothenic Acid (B5) and Biotin (B7) food sources
Whole grains and cereals, nuts, legumes, peanut butter, meat, milk, eggs
Biotin also synthesized by intestinal bacteria
Pantothenic Acid (B5) underconsumption
"Burning feet" syndrome
Biotin (B7) underconsumption
Hair loss, skin rash, fatigue, nausea, depression
Deficiency is rare but can occur from eating too much raw egg whites, which prevents biotin absorption
Vitamin C/ Ascorbic acid function
Coenzyme to synthesize and use certain amino acids
Needed to make collagen
antioxidant
Helps absorb iron from plant foods
Breaks down histamine (cause of inflammation)
immune system
Vitamin C food sources
Fruits and vegetables (tomatoes, peppers, broccoli, oranges, cantaloupe)
Vitamin C overconsumption
Can cause nausea, stomach cramps, and diarrhea
Vitamin C underconsumption
Scurvy – swollen and bleeding gums, rough rash on skin, coiled or curly arm hairs, wounds that won’t heal
May result in skin hemorrhages (purple-colored spots on skin or mucous membranes like in the mouth)
Vitamin A
Provides the yellow-red pigment in foods like carrots and butternut squash and is essential for eye health