LAT 01: Animal Research and Funding and Program Oversight

LAT

Every 6 months the IACUC must create a report summarizing the findings of the semiannual program review and submit it to ______. 

the Institutional Official (IO)

What is a grant application used to request?

Research money

A document that outlines the steps required to clean an animal room is called a:

standard operating procedure. (SOP)

Federal agencies are the only source of grant money. T/F?

False

What is the full name for the acronym PAM?

Post-approval monitoring program

Which of the following is a primary duty of the IACUC? 

A. Review animal welfare concerns

B. Provide accreditation of animal research programs

C. Review research grant applications

D. Publish research data in peer-reviewed journals

A. Review animal welfare concerns

An institution's animal care and use program and facility should be subjected to review how frequently? 

Every 6 months (Semi-Annually)

Why are scientific studies published in a peer-reviewed journal? 

To inform other scientists about the study results

Which entity in AAALAC International approves an institution's application for accreditation?

Council on Accreditation

Which statement regarding private funding sources is FALSE? 

A. Donations used to fund research may come with conditions.

B. Private corporations may contract out research to universities.

C. Private foundations are a funding source for research.

D. Researchers working for private companies do not need to compete for funding.

D. Researchers working for private companies do not need to compete for funding.

Who must approve an animal use protocol before a study that involves animals can begin? 

Institutional Animal Care and Use Committee (IACUC)

The NIH is the primary funding agency for what type of research?

Biomedical research

Who makes the decision of how to handle any serious deficiencies found during post-approval monitoring?

IACUC

Which mandate states that protocols for USDA-covered species may only be approved for 1 year? 

Animal Welfare Regulations (AWR)

When applying for AAALAC accreditation, the institution submits a detailed document outlining the animal care program called a ___?

Program description

Who is responsible for appointing members to the IACUC? 

Chief Executive Officer

Suspending an animal care and use protocol requires the notification of which agencies?

AAALAC International, OLAW, USDA

Before a new drug is tested on human subjects, the drug is tested on animals in a phase that is called __________ testing. 

preclinical

Which of the following is NOT a member of the IACUC? 

A. Attending Veterinarian

B. Chief Executive Officer

C. Provost

D. IACUC Chair

B. Chief Executive Officer

What does AAALAC stand for?

Association for Assessment and Accreditation of Laboratory Animal Care, International.

What does USDA stand for?

United States Department of Agriculture

Who is the inspecting arm for the AWA?

USDA

What does AWA stand for

Animal Welfare Act

What does IACUC stand for?

Institutional Animal Care and Use Committee

IACUC’s are mandated by which entities?

AWA and PHS policy

How often does IACUC have to review and approve animal research protocols for USDA covered species? For non-USDA species?

One year or annually for USDA covered species / 1-3 years for non-USDA covered species

How frequently must PIs review/update their animal use protocols?

Annually

How frequently must PIs apply for a continuation(renew) of an already established animal use protocol?

Every three years

What is the frequency of IACUC inspections?

every 6 months

What is the frequency of AAALAC site inspections and program evaluations?

every three years

What document does AAALAC use for accreditation compliance?

The Guide

Which mandate requires five IACUC members? List them.

PHS Policy

-Chair person

-Scientist with animal research experience

-Vet with lab medicine experience

-Non-scientist

-Public Member not affiliated with institution

Which mandate requires four IACUC members? List them.

The Guide

-Vet with lab medicine experience

-Scientist with animal research experience

-Non-scientist

-Public Member

Which mandate requires three IACUC members? List them.

AWA and Regs

-Chair person

-Vet with lab medicine experience

-Public Member

What does PHS stand for?

Public Health Service Policy

What does AWR stand for?

Animal welfare regulations