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Biological systems are organized hierarchically:
cells → tissues → organs → organ systems → organisms
Cells are the fundamental _______
unit of life,
Cells contain smaller structures called _______
organelles
what are the two main types of cells?
prokaryotic (no nucleus, no membrane-bound organelles) and eukaryotic (have nucleus and membrane-bound organelles)
what does the cell membrane (plasma membrane) control?
selective permeability, maintaining homeostasis
whats cytoplasm?
a jellylike substance supporting organelles inside the cell
whats the cytoskeleton?
provides structural support and aids in cell movement
what do ribosomes do?
synthesize proteins also found in both prokaryotic and eukaryotic cells
what is the nucleus?
the control center in eukaryotic cells, housing DNA and nucleolus (site of ribosome assembly)
Endoplasmic reticulum (ER) ________ molecules
processes and transports
rough ER has ________
ribosomes and produces proteins
smooth ER lacks _______ nd is involved in lipid synthesis and detoxification
ribosomes
what is the Golgi apparatus?
it modifies, sorts, and packages proteins and lipids for transport or secretion
Mitochondria generate ATP energy through _______
cellular respiration, using glucose and oxygen also known as the "powerhouse" of the cell
What is the purpose of chloroplast in plant cells?
perform photosynthesis, producing glucose using sunlight
lysosomes digest ______
cellular waste and foreign invaders
vacuoles _________
store nutrients, waste, and maintain cell pressure (especially in plants)
how do cells form?
only from pre-existing cells, emphasizing replication
cell
Basic unit of life in all organisms
Organelle
specialized structures within cells performing specific functions
Prokaryote
Cell without a nucleus or membrane-bound organelles (e.g., bacteria)
Eukaryote
Cell with a nucleus and membrane-bound organelles (e.g., plants, animals)
Plasma membrane
Selectively permeable barrier controlling substance movement in and out of the cell
Cytoplasm
Gel-like substance inside the cell holding organelles
Cytoskeleton
Network of fibers providing structure and movement to the cell
Ribosomes
site of protein synthesis
Nucleus
Control center of the cell
Nucleolus
Found inside the nucleus and produces ribosomes
Endoplasmic Reticulum (ER)
Membrane system for protein and lipid synthesis and transport
Rough ER
studded with ribosomes, involved in protein synthesis
Smooth ER
no ribosomes and makes lipids
Golgi apparatus
modifies, sorts, and packages proteins and lipids
Mitochondria
Powerhouse of the cell, organelle that is the site of ATP (energy) production
ATP
adenosine triphosphate, main energy currency of the cell
Chloroplast
Site of photosynthesis
Lysosomes
containing enzymes to digest cellular waste and invaders
Vacuole
Fluid-filled sac for storage and maintaining pressure
Homeostasis
Stable internal environment maintained by the cell
Prokaryotic cells lack ________
nucleus and membrane-bound organelles
bacteria is ______
unicellular prokaryotes
humans are _____
multicellular eukaryotes
Eukaryotic cells have ______
nucleus and membrane bound organelles
What does mitosis produce?
two identical daughter cells
What does meiosis produce?
haploid gametes
What type of cell do both mitosis and meiosis start from?
diploid (2N) cell
What are the stages of both mitosis and meiosis?
Prophase, Metaphase, Anaphase, Telophase (meiosis repeats these stages twice)
What separates in mitosis vs. meiosis I?
Mitosis: sister chromatids separate
Meiosis I: homologous chromosomes separate
During which phase does crossing over occur?
Prophase I of meiosis
What is the result of crossing over?
genetic diversity
How many chromosomes do humans have?
46 total (23 pairs)
How many chromosomes are in gametes?
23
What happens during interphase?
chromosomes replicate, but chromatids stay joined at the centromere
What are the outcomes of mitosis and meiosis?
Mitosis: 2 identical diploid cells Meiosis: 4 unique haploid cells.
Where do homologous chromosomes pair?
In prophase I of meiosis
How do chromosomes line up in metaphase for mitosis vs. meiosis I?
Mitosis: singly Meiosis I: in pairs
What enzyme starts transcription in protein synthesis?
RNA polymerase
What is mitosis?
Cell division producing two identical diploid body cells
What is meiosis?
Cell division producing four genetically diverse haploid gametes
diploid (2N)
2 sets of chromosomes
haploid (N)
one set of chromosomes, typical of gametes
What is a chromatid?
half of a duplicated chromosome
What is a centromere?
The region where sister chromatids are joined
What are homologous chromosomes?
Chromosome pairs (one from each parent) similar in size and gene location.
What is crossing over
Exchange of genetic material between homologous chromosomes during meiosis
What are gametes?
sex cells (sperm and egg)
What is DNA?
deoxyribonucleic acid, genetic DNA
What is the structure of DNA?
Double helix made of nucleotides with sugar-phosphate backbone
What are the DNA base pairing rules?
A - T, C-G
What is a gene?
segment of DNA that codes for a protein
What is gene regulation?
Mechanisms that control when and how genes are expressed
How is DNA packaged?
It wraps around histone proteins to form chromosomes
What is RNA?
Ribonucleic acid, used to decode DNA instructions for protein synthesis
What are the three types of RNA?
mRNA, tRNA, rRNA
What are codons and anticodons?
Codons: 3-base mRNA sequences Anticodons: complementary 3-base tRNA sequences
What base does RNA use instead of thymine (T)?
Uracil (U)
Where is RNA found?
nucleus and cytoplasm
What happens during transcription?
DNA is converted to mRNA in the nucleus
What happens during translation?
The ribosome uses mRNA and tRNA to assemble amino acids into proteins
What is the sequence of protein synthesis?
DNA -> RNA -> Protein
What do stop codons do?
Signal the end of protein synthesis
whats the RNA pairing?
A-U
What happens when sperm and egg fuse?
form a diploid zygote
What is the role of meiosis in heredity?
Creates genetic variation through crossing over and random assortment
PAT in cell divison phase=
Prophase, Anaphase, Telophase